Non-conventional yeast cell factories for sustainable bioprocesses

The non-conventional yeasts Kluyveromyces lactis, Yarrowia lipolytica, Ogataea polymorpha and Pichia pastoris have been developed as eukaryotic expression hosts because of their desirable growth characteristics, including inhibitor and thermo-tolerance, utilisation of diverse carbon substrates and h...

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Veröffentlicht in:FEMS microbiology letters 2018-11, Vol.365 (21), p.1
Hauptverfasser: Rebello, Sharrel, Abraham, Amith, Madhavan, Aravind, Sindhu, Raveendran, Binod, Parameswaran, Karthika Bahuleyan, Arun, Aneesh, Embalil Mathachan, Pandey, Ashok
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container_issue 21
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container_title FEMS microbiology letters
container_volume 365
creator Rebello, Sharrel
Abraham, Amith
Madhavan, Aravind
Sindhu, Raveendran
Binod, Parameswaran
Karthika Bahuleyan, Arun
Aneesh, Embalil Mathachan
Pandey, Ashok
description The non-conventional yeasts Kluyveromyces lactis, Yarrowia lipolytica, Ogataea polymorpha and Pichia pastoris have been developed as eukaryotic expression hosts because of their desirable growth characteristics, including inhibitor and thermo-tolerance, utilisation of diverse carbon substrates and high amount of extracellular protein secretion. These yeasts already have established in the heterologous production of vaccines, therapeutic proteins, food additives and bio-renewable chemicals, but recent advances in the genetic tool box have the potential to greatly expand and diversify their impact on biotechnology. The diversity of these yeasts includes many strains possessing highly useful, and in some cases even uncommon, metabolic capabilities potentially helpful for the bioprocess industry. This review outlines the recent updates of non-conventional yeast in sustainable bioprocesses.
doi_str_mv 10.1093/femsle/fny222
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source Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection
subjects Biotechnology
Brewer's yeast
Carbon sources
Food additives
Microbiology
Physiological aspects
Proteins
Substrates
Vaccines
Yeast
Yeasts
title Non-conventional yeast cell factories for sustainable bioprocesses
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