Bioinspired structural transition of synthetic polymers through biomolecular ligand binding

Inspired by ligand binding-triggered structural transition of biopolymers in living systems, we demonstrated the structural transition of thermoresponsive poly( N -isopropylacrylamide) through specific ligand binding of artificially evolved peptides to the polymer. The bioinspired structural transit...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2018-10, Vol.54 (85), p.126-129
Hauptverfasser: Suzuki, Seigo, Sawada, Toshiki, Ishizone, Takashi, Serizawa, Takeshi
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container_issue 85
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container_title Chemical communications (Cambridge, England)
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creator Suzuki, Seigo
Sawada, Toshiki
Ishizone, Takashi
Serizawa, Takeshi
description Inspired by ligand binding-triggered structural transition of biopolymers in living systems, we demonstrated the structural transition of thermoresponsive poly( N -isopropylacrylamide) through specific ligand binding of artificially evolved peptides to the polymer. The bioinspired structural transition of thermoresponsive poly( N -isopropylacrylamide) was demonstrated by specific ligand binding of artificially evolved peptides to the polymer.
doi_str_mv 10.1039/c8cc06232c
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source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Absorption spectra
Binding
Biopolymers
Fluorescence
Isopropylacrylamide
Ligands
Molecular structure
NMR
Nuclear magnetic resonance
Peptides
Size exclusion chromatography
title Bioinspired structural transition of synthetic polymers through biomolecular ligand binding
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