Comparative analysis of estrogenic activity in sewage treatment plant effluents involving three in vitro assays and chemical analysis of steroids

In this study, we assessed and compared the suitability of three in vitro screening tools for the measurement of estrogenic activity in sewage treatment plant effluents (STPEs). These assays were the yeast estrogen screen (YES), production of zona radiata proteins (ZRPs) in trout hepatocytes, and th...

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Veröffentlicht in:	Environmental toxicology and chemistry 2004-04, Vol.23 (4), p.857-864
Hauptverfasser:	Rutishauser, Barbara V., Pesonen, Maija, Escher, Beate I., Ackermann, Gabriele E., Aerni, Hans-Rudolf, Suter, Marc J.-F., Eggen, Rik I.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agnatha. Pisces Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences Biological Assay - methods Cell Line Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on vertebrates Egg Proteins - biosynthesis Endocrine disrupters Estrogens - analysis Estrogens - pharmacology Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects General aspects Genes, Reporter Gonads - cytology Hepatocytes In vitro assays Oncorhynchus mykiss Sensitivity and Specificity Sewage - chemistry Sewage treatment plant effluents Steroid analysis Transfection Trout Water Pollutants, Chemical - analysis Water Pollutants, Chemical - pharmacology Yeasts
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