Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population

BACKGROUND. It is believed that acetaldehyde plays an important role in alcohol-related carcinogenesis; although current epidemiologic studies have provided inconsistent findings on the association between alcohol consumption and the risk of lung cancer. METHODS. To clarify the hypothesis that genet...

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Veröffentlicht in:	Cancer 2007-07, Vol.110 (2), p.353-362
Hauptverfasser:	Minegishi, Yuji, Tsukino, Hiromasa, Muto, Manabu, Goto, Koichi, Gemma, Akihiko, Tsugane, Shoichiro, Kudoh, Shoji, Nishiwaki, Yutaka, Esumi, Hiroyasu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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