Lanthanide‐Catalyzed Tandem Insertion of Secondary Amines with 2‐Alkynylbenzonitriles: Synthesis of Aminoisoindoles

A lanthanide‐catalyzed intermolecular hydroamination of 2‐alkynylbenzonitriles with secondary amines has been disclosed, providing a streamlined access to a range of aminoisoindoles in moderate to excellent yields. The salient features of this reaction include high bond‐formation efficiency, mild re...

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Veröffentlicht in:	Chemistry, an Asian journal an Asian journal, 2018-12, Vol.13 (23), p.3681-3690
Hauptverfasser:	Ye, Pengqing, Shao, Yinlin, Xie, Leping, Shen, Keting, Cheng, Tianxing, Chen, Jiuxi
Format:	Artikel
Sprache:	eng
Schlagworte:	2-alkynylbenzonitriles Amines aminoisoindoles Chemical synthesis Chemistry Functional groups Insertion lanthanide-catalyzed Nitrogen secondary amines tandem reaction
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