Contribution of endogenously formed arachidonic acid in the presynaptic facilitatory effects of NMDA and carbachol on dopamine release in the mouse striatum

Arachidonic acid stimulated the release of [3H]‐dopamine from striatal microdiscs in a concentration‐dependent and partially calcium‐dependent manner. Inhibitors of cytosolic and membrane‐bound phospholipase A2 were used to determine whether endogenously formed arachidonic acid also contributes to t...

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Veröffentlicht in:	The European journal of neuroscience 1999-04, Vol.11 (4), p.1292-1300
Hauptverfasser:	L'hirondel, M., Chéramy, A., Artaud, F., Godeheu, G., Glowinski, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Arachidonic Acid - biosynthesis Arachidonic Acid - physiology Carbachol - pharmacology cholinergic agonists Corpus Striatum - drug effects Corpus Striatum - metabolism Dopamine Dopamine - metabolism Drug Resistance Drug Synergism Enzyme Inhibitors - pharmacology glutamatergic agonists Kinases Magnesium - physiology Male Mice N-Methylaspartate - pharmacology phospholipase A2 inhibitors Phospholipases A - antagonists & inhibitors Phospholipases A2 Potassium Presynaptic Terminals - drug effects Quinacrine - pharmacology slices Synapses - drug effects Synapses - metabolism synaptosomes Tetrodotoxin - pharmacology
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