Development and Application of an Electron Spin Resonance Spectrometry Method for the Determination of Oxygen Free Radical Formation by Particulate Matter
Exposure to increased levels of ambient particulate matter (PM) are associated with several health effects, including cardiopulmonary diseases. The formation of reactive oxygen species (ROS) is thought to play an important role in the induction of these health effects. To quantify the ROS generating...
Gespeichert in:
| Veröffentlicht in: | Environmental science & technology 2005-11, Vol.39 (21), p.8420-8426 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 8426 |
|---|---|
| container_issue | 21 |
| container_start_page | 8420 |
| container_title | Environmental science & technology |
| container_volume | 39 |
| creator | Briedé, Jacob J de Kok, Theo M. C. M Hogervorst, Janneke G. F Moonen, Edwin J. C op den Camp, Clif L. B Kleinjans, Jos C. S |
| description | Exposure to increased levels of ambient particulate matter (PM) are associated with several health effects, including cardiopulmonary diseases. The formation of reactive oxygen species (ROS) is thought to play an important role in the induction of these health effects. To quantify the ROS generating capacity of PM, we developed an improved electron spin resonance (ESR) spectrometry-based method. ROS formation was measured directly on PM-containing filters, thereby avoiding the selective extraction of components and loss of material or reactivity, which is likely to occur during filter extraction. Also, ascorbic acid was added to stimulate ROS formation. This method was applied to PM10 samples originating from different sources. The radical generating capacity of PM10 from both gasoline and diesel engine exhaust was significantly higher as compared to that of PM10 from ambient or indoor air. Furthermore, in urban PM10 and PM2.5, ROS-generating capacity significantly correlated with concentrations of polycyclic aromatic hydrocarbon content and particular transition metals. This indicates that this improved ESR method may be a valuable tool for evaluating the relationship between ROS formation by PM and the adverse health effects associated with this type of air pollution. |
| doi_str_mv | 10.1021/es0485311 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_21033487</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>924474141</sourcerecordid><originalsourceid>FETCH-LOGICAL-a439t-a0c17b3c22799d743055bee4cabbf03ce32e02c50c4f25dc88be273ec74d5c393</originalsourceid><addsrcrecordid>eNplkdtu1DAQhi0EokvhghdAFhJIXAR8jJPLqu0CUg-rthzuLMeZ0JTEDraDuq_C02LY1a4EV9aMP_8z_n-EnlPylhJG30EkopKc0gdoQSUjhawkfYgWhFBe1Lz8eoCexHhHCGGcVI_RAS1ZLaqKLdCvE_gJg59GcAkb1-KjaRp6a1LvHfZdbuHTAWwKubyeeoevIHpnnIVc_u2PkMIan0O69S3ufMDpFvAJJAhj73Y6l_frb-DwMgDgK9PmCQNe-jBugGaNVyak3s6DSYDPTcrPn6JHnRkiPNueh-jT8vTm-ENxdvn-4_HRWWEEr1NhiKWq4ZYxVdetEpxI2QAIa5qmI9wCZ0CYlcSKjsnWVlUDTHGwSrTS8pofotcb3Sn4HzPEpMc-WhgG48DPUTNKOBeVyuDLf8A7PweXd9PZV8rLui4z9GYD2eBjDNDpKfSjCWtNif6Tlt6lldkXW8G5GaHdk9t4MvBqC5iYHetCNr6Pe04xIWgtMldsuD4muN_dm_Bdl4orqW9W15rIL5_VxarWF3tdY-P-E_8v-BvSfbkm</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>230136996</pqid></control><display><type>article</type><title>Development and Application of an Electron Spin Resonance Spectrometry Method for the Determination of Oxygen Free Radical Formation by Particulate Matter</title><source>MEDLINE</source><source>ACS Publications</source><creator>Briedé, Jacob J ; de Kok, Theo M. C. M ; Hogervorst, Janneke G. F ; Moonen, Edwin J. C ; op den Camp, Clif L. B ; Kleinjans, Jos C. S</creator><creatorcontrib>Briedé, Jacob J ; de Kok, Theo M. C. M ; Hogervorst, Janneke G. F ; Moonen, Edwin J. C ; op den Camp, Clif L. B ; Kleinjans, Jos C. S</creatorcontrib><description>Exposure to increased levels of ambient particulate matter (PM) are associated with several health effects, including cardiopulmonary diseases. The formation of reactive oxygen species (ROS) is thought to play an important role in the induction of these health effects. To quantify the ROS generating capacity of PM, we developed an improved electron spin resonance (ESR) spectrometry-based method. ROS formation was measured directly on PM-containing filters, thereby avoiding the selective extraction of components and loss of material or reactivity, which is likely to occur during filter extraction. Also, ascorbic acid was added to stimulate ROS formation. This method was applied to PM10 samples originating from different sources. The radical generating capacity of PM10 from both gasoline and diesel engine exhaust was significantly higher as compared to that of PM10 from ambient or indoor air. Furthermore, in urban PM10 and PM2.5, ROS-generating capacity significantly correlated with concentrations of polycyclic aromatic hydrocarbon content and particular transition metals. This indicates that this improved ESR method may be a valuable tool for evaluating the relationship between ROS formation by PM and the adverse health effects associated with this type of air pollution.</description><identifier>ISSN: 0013-936X</identifier><identifier>EISSN: 1520-5851</identifier><identifier>DOI: 10.1021/es0485311</identifier><identifier>PMID: 16294882</identifier><identifier>CODEN: ESTHAG</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Air pollution ; Air. Soil. Water. Waste. Feeding ; Airborne particulates ; Applied sciences ; Atmospheric pollution ; Biological and medical sciences ; Electron Spin Resonance Spectroscopy - methods ; Electrons ; Environment. Living conditions ; Environmental Pollutants ; Exact sciences and technology ; Free Radicals ; Medical sciences ; Particle Size ; Pollutants physicochemistry study: properties, effects, reactions, transport and distribution ; Pollution ; Polycyclic Compounds - analysis ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Reactive Oxygen Species - chemistry ; Scientific imaging ; Spectrum analysis</subject><ispartof>Environmental science & technology, 2005-11, Vol.39 (21), p.8420-8426</ispartof><rights>Copyright © 2005 American Chemical Society</rights><rights>2006 INIST-CNRS</rights><rights>Copyright American Chemical Society Nov 1, 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a439t-a0c17b3c22799d743055bee4cabbf03ce32e02c50c4f25dc88be273ec74d5c393</citedby><cites>FETCH-LOGICAL-a439t-a0c17b3c22799d743055bee4cabbf03ce32e02c50c4f25dc88be273ec74d5c393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/es0485311$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/es0485311$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,2764,27075,27923,27924,56737,56787</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17244194$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16294882$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Briedé, Jacob J</creatorcontrib><creatorcontrib>de Kok, Theo M. C. M</creatorcontrib><creatorcontrib>Hogervorst, Janneke G. F</creatorcontrib><creatorcontrib>Moonen, Edwin J. C</creatorcontrib><creatorcontrib>op den Camp, Clif L. B</creatorcontrib><creatorcontrib>Kleinjans, Jos C. S</creatorcontrib><title>Development and Application of an Electron Spin Resonance Spectrometry Method for the Determination of Oxygen Free Radical Formation by Particulate Matter</title><title>Environmental science & technology</title><addtitle>Environ. Sci. Technol</addtitle><description>Exposure to increased levels of ambient particulate matter (PM) are associated with several health effects, including cardiopulmonary diseases. The formation of reactive oxygen species (ROS) is thought to play an important role in the induction of these health effects. To quantify the ROS generating capacity of PM, we developed an improved electron spin resonance (ESR) spectrometry-based method. ROS formation was measured directly on PM-containing filters, thereby avoiding the selective extraction of components and loss of material or reactivity, which is likely to occur during filter extraction. Also, ascorbic acid was added to stimulate ROS formation. This method was applied to PM10 samples originating from different sources. The radical generating capacity of PM10 from both gasoline and diesel engine exhaust was significantly higher as compared to that of PM10 from ambient or indoor air. Furthermore, in urban PM10 and PM2.5, ROS-generating capacity significantly correlated with concentrations of polycyclic aromatic hydrocarbon content and particular transition metals. This indicates that this improved ESR method may be a valuable tool for evaluating the relationship between ROS formation by PM and the adverse health effects associated with this type of air pollution.</description><subject>Air pollution</subject><subject>Air. Soil. Water. Waste. Feeding</subject><subject>Airborne particulates</subject><subject>Applied sciences</subject><subject>Atmospheric pollution</subject><subject>Biological and medical sciences</subject><subject>Electron Spin Resonance Spectroscopy - methods</subject><subject>Electrons</subject><subject>Environment. Living conditions</subject><subject>Environmental Pollutants</subject><subject>Exact sciences and technology</subject><subject>Free Radicals</subject><subject>Medical sciences</subject><subject>Particle Size</subject><subject>Pollutants physicochemistry study: properties, effects, reactions, transport and distribution</subject><subject>Pollution</subject><subject>Polycyclic Compounds - analysis</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Reactive Oxygen Species - chemistry</subject><subject>Scientific imaging</subject><subject>Spectrum analysis</subject><issn>0013-936X</issn><issn>1520-5851</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkdtu1DAQhi0EokvhghdAFhJIXAR8jJPLqu0CUg-rthzuLMeZ0JTEDraDuq_C02LY1a4EV9aMP_8z_n-EnlPylhJG30EkopKc0gdoQSUjhawkfYgWhFBe1Lz8eoCexHhHCGGcVI_RAS1ZLaqKLdCvE_gJg59GcAkb1-KjaRp6a1LvHfZdbuHTAWwKubyeeoevIHpnnIVc_u2PkMIan0O69S3ufMDpFvAJJAhj73Y6l_frb-DwMgDgK9PmCQNe-jBugGaNVyak3s6DSYDPTcrPn6JHnRkiPNueh-jT8vTm-ENxdvn-4_HRWWEEr1NhiKWq4ZYxVdetEpxI2QAIa5qmI9wCZ0CYlcSKjsnWVlUDTHGwSrTS8pofotcb3Sn4HzPEpMc-WhgG48DPUTNKOBeVyuDLf8A7PweXd9PZV8rLui4z9GYD2eBjDNDpKfSjCWtNif6Tlt6lldkXW8G5GaHdk9t4MvBqC5iYHetCNr6Pe04xIWgtMldsuD4muN_dm_Bdl4orqW9W15rIL5_VxarWF3tdY-P-E_8v-BvSfbkm</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>Briedé, Jacob J</creator><creator>de Kok, Theo M. C. M</creator><creator>Hogervorst, Janneke G. F</creator><creator>Moonen, Edwin J. C</creator><creator>op den Camp, Clif L. B</creator><creator>Kleinjans, Jos C. S</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>SOI</scope><scope>7TG</scope><scope>7TV</scope><scope>KL.</scope></search><sort><creationdate>20051101</creationdate><title>Development and Application of an Electron Spin Resonance Spectrometry Method for the Determination of Oxygen Free Radical Formation by Particulate Matter</title><author>Briedé, Jacob J ; de Kok, Theo M. C. M ; Hogervorst, Janneke G. F ; Moonen, Edwin J. C ; op den Camp, Clif L. B ; Kleinjans, Jos C. S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a439t-a0c17b3c22799d743055bee4cabbf03ce32e02c50c4f25dc88be273ec74d5c393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Air pollution</topic><topic>Air. Soil. Water. Waste. Feeding</topic><topic>Airborne particulates</topic><topic>Applied sciences</topic><topic>Atmospheric pollution</topic><topic>Biological and medical sciences</topic><topic>Electron Spin Resonance Spectroscopy - methods</topic><topic>Electrons</topic><topic>Environment. Living conditions</topic><topic>Environmental Pollutants</topic><topic>Exact sciences and technology</topic><topic>Free Radicals</topic><topic>Medical sciences</topic><topic>Particle Size</topic><topic>Pollutants physicochemistry study: properties, effects, reactions, transport and distribution</topic><topic>Pollution</topic><topic>Polycyclic Compounds - analysis</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Reactive Oxygen Species - chemistry</topic><topic>Scientific imaging</topic><topic>Spectrum analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Briedé, Jacob J</creatorcontrib><creatorcontrib>de Kok, Theo M. C. M</creatorcontrib><creatorcontrib>Hogervorst, Janneke G. F</creatorcontrib><creatorcontrib>Moonen, Edwin J. C</creatorcontrib><creatorcontrib>op den Camp, Clif L. B</creatorcontrib><creatorcontrib>Kleinjans, Jos C. S</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Pollution Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><jtitle>Environmental science & technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Briedé, Jacob J</au><au>de Kok, Theo M. C. M</au><au>Hogervorst, Janneke G. F</au><au>Moonen, Edwin J. C</au><au>op den Camp, Clif L. B</au><au>Kleinjans, Jos C. S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development and Application of an Electron Spin Resonance Spectrometry Method for the Determination of Oxygen Free Radical Formation by Particulate Matter</atitle><jtitle>Environmental science & technology</jtitle><addtitle>Environ. Sci. Technol</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>39</volume><issue>21</issue><spage>8420</spage><epage>8426</epage><pages>8420-8426</pages><issn>0013-936X</issn><eissn>1520-5851</eissn><coden>ESTHAG</coden><abstract>Exposure to increased levels of ambient particulate matter (PM) are associated with several health effects, including cardiopulmonary diseases. The formation of reactive oxygen species (ROS) is thought to play an important role in the induction of these health effects. To quantify the ROS generating capacity of PM, we developed an improved electron spin resonance (ESR) spectrometry-based method. ROS formation was measured directly on PM-containing filters, thereby avoiding the selective extraction of components and loss of material or reactivity, which is likely to occur during filter extraction. Also, ascorbic acid was added to stimulate ROS formation. This method was applied to PM10 samples originating from different sources. The radical generating capacity of PM10 from both gasoline and diesel engine exhaust was significantly higher as compared to that of PM10 from ambient or indoor air. Furthermore, in urban PM10 and PM2.5, ROS-generating capacity significantly correlated with concentrations of polycyclic aromatic hydrocarbon content and particular transition metals. This indicates that this improved ESR method may be a valuable tool for evaluating the relationship between ROS formation by PM and the adverse health effects associated with this type of air pollution.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>16294882</pmid><doi>10.1021/es0485311</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0013-936X |
| ispartof | Environmental science & technology, 2005-11, Vol.39 (21), p.8420-8426 |
| issn | 0013-936X 1520-5851 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_21033487 |
| source | MEDLINE; ACS Publications |
| subjects | Air pollution Air. Soil. Water. Waste. Feeding Airborne particulates Applied sciences Atmospheric pollution Biological and medical sciences Electron Spin Resonance Spectroscopy - methods Electrons Environment. Living conditions Environmental Pollutants Exact sciences and technology Free Radicals Medical sciences Particle Size Pollutants physicochemistry study: properties, effects, reactions, transport and distribution Pollution Polycyclic Compounds - analysis Public health. Hygiene Public health. Hygiene-occupational medicine Reactive Oxygen Species - chemistry Scientific imaging Spectrum analysis |
| title | Development and Application of an Electron Spin Resonance Spectrometry Method for the Determination of Oxygen Free Radical Formation by Particulate Matter |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T15%3A34%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20and%20Application%20of%20an%20Electron%20Spin%20Resonance%20Spectrometry%20Method%20for%20the%20Determination%20of%20Oxygen%20Free%20Radical%20Formation%20by%20Particulate%20Matter&rft.jtitle=Environmental%20science%20&%20technology&rft.au=Bried%C3%A9,%20Jacob%20J&rft.date=2005-11-01&rft.volume=39&rft.issue=21&rft.spage=8420&rft.epage=8426&rft.pages=8420-8426&rft.issn=0013-936X&rft.eissn=1520-5851&rft.coden=ESTHAG&rft_id=info:doi/10.1021/es0485311&rft_dat=%3Cproquest_cross%3E924474141%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=230136996&rft_id=info:pmid/16294882&rfr_iscdi=true |