Recent Advances in the Studies of Molecular Mechanisms Regulating Multidrug Resistance in Cancer Cells

—Here we present new approaches to better understanding multidrug resistance (MDR) development in cancer cells, such as identification of components of a complex process of MDR evolution. Recent advances in the studies of MDR are discussed: 1) chemotherapy agents might be involved in the selection o...

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Veröffentlicht in:	Biochemistry (Moscow) 2018-07, Vol.83 (7), p.779-786
Hauptverfasser:	Stavrovskaya, A. A., Rybalkina, E. Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporter Apoptosis ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Biochemistry Biological research Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cancer Cancer cells Cell Communication - drug effects Cell interactions Chemotherapy Drug resistance Drug Resistance, Multiple Drug Resistance, Neoplasm Evolution Glycoproteins Humans Life Sciences MDR1 protein Mechanotransduction Microbiology Molecular chains Molecular mechanics Molecular modelling Multidrug resistance Multidrug resistant organisms Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Neoplastic Stem Cells - drug effects Neoplastic Stem Cells - pathology P-Glycoprotein Physiological aspects Proteins Review Stem cells Transcription Tumorigenicity
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