Incidence of PTLD in Pediatric Renal Transplant Recipients Receiving Basiliximab, Calcineurin Inhibitor, Sirolimus and Steroids

Pediatric renal transplant recipients were enrolled in a multicenter, randomized, double‐blind trial of steroid withdrawal. Subjects received basiliximab, calcineurin inhibitor, sirolimus and steroids. Of 274 subjects enrolled, 19 (6.9%) subjects developed posttransplant lymphoproliferative disorder...

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Veröffentlicht in:	American journal of transplantation 2008-05, Vol.8 (5), p.984-989
Hauptverfasser:	McDonald, R. A., Smith, J. M., Ho, M., Lindblad, R., Ikle, D., Grimm, P., Wyatt, R., Arar, M., Liereman, D., Bridges, N., Harmon, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenal Cortex Hormones - adverse effects Adrenal Cortex Hormones - therapeutic use Adult Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Basiliximab Biological and medical sciences Child Child, Preschool Cyclosporine - therapeutic use Double-Blind Method EBV Epidemiology Epstein-Barr virus Female General aspects Hematologic and hematopoietic diseases Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Infant Kidney Transplantation - adverse effects Kidney Transplantation - immunology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoproliferative Disorders - epidemiology Male Medical sciences Multivariate Analysis pediatric Postoperative Complications - prevention & control PTLD Public health. Hygiene Public health. Hygiene-occupational medicine Recombinant Fusion Proteins - adverse effects Recombinant Fusion Proteins - therapeutic use renal transplant Sirolimus - adverse effects Sirolimus - therapeutic use Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tacrolimus - therapeutic use
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