Requirements for Surface Expression and Function of Adhesin P1 from Streptococcus mutans

In this report, we define requirements for the successful translocation and functional maturation of the adhesin P1 of Streptococcus mutans. Conformational epitopes recognized by anti-P1 monoclonal antibodies (MAbs) were further characterized, thus facilitating the use of particular MAbs as tools to...

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Veröffentlicht in:	Infection and Immunity 2008-06, Vol.76 (6), p.2456-2468
Hauptverfasser:	Crowley, Paula J, Seifert, Trevor B, Isoda, Ryutaro, van Tilburg, Marloes, Oli, Monika W, Robinette, Rebekah A, McArthur, William P, Bleiweis, Arnold S, Brady, L. Jeannine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Adhesins, Bacterial - genetics Adhesins, Bacterial - metabolism Animals Bacterial Adhesion Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Down-Regulation Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Bacterial - physiology Mice Microbiology Miscellaneous Molecular Pathogenesis Mutation Protein Conformation Protein Transport Rabbits Serine Endopeptidases - genetics Serine Endopeptidases - metabolism Streptococcus mutans Streptococcus mutans - genetics Streptococcus mutans - metabolism
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