Crystal Structure of the RRM Domain of Poly(A)-Specific Ribonuclease Reveals a Novel m super(7)G-Cap-Binding Mode
Poly(A)-specific ribonuclease (PARN) is a processive 3'-exoribonuclease involved in the decay of eukaryotic mRNAs. Interestingly, PARN interacts not only with the 3' end of the mRNA but also with its 5' end as PARN contains an RRM domain that specifically binds both the poly(A) tail a...
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| Veröffentlicht in: | Journal of molecular biology 2008-10, Vol.382 (4), p.827-834 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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