Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion sho...
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| Veröffentlicht in: | The Journal of the Royal College of Physicians of Edinburgh 2018-09, Vol.48 (3), p.239-241 |
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| container_title | The Journal of the Royal College of Physicians of Edinburgh |
| container_volume | 48 |
| creator | Shahedah, K K Khoo, C S Wan Nur Nafisah, W Y Ng, C F Noor Ashikin, I Mohd Naim, M Y Syazarina Sharis, O Rozman, Z Wan Asyraf, W Z |
| description | A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA. She was discharged with NIHSS of 2, and at 3-month follow up her Modified Rankin Scale was 0. We demonstrated a successful reperfusion and excellent clinical recovery with intravenous thrombolysis in a patient who presented with a wake-up stroke with underlying valvular atrial fibrillation despite evidence of large vessel occlusion. |
| doi_str_mv | 10.4997/JRCPE.2018.308 |
| format | Article |
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| ispartof | The Journal of the Royal College of Physicians of Edinburgh, 2018-09, Vol.48 (3), p.239-241 |
| issn | 1478-2715 2042-8189 |
| language | eng |
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| source | SAGE Complete A-Z List; Alma/SFX Local Collection |
| title | Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation |
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