Tissue Plasminogen Activator-Porous Magnetic Microrods for Targeted Thrombolytic Therapy after Ischemic Stroke

Tissue plasminogen activator (tPA) is the only FDA approved thrombolytic drug for acute ischemic stroke but concerns regarding its limitations remain. Here, we developed a new strategy by incorporating tPA into porous magnetic iron oxide (Fe3O4)-microrods (tPA-MRs) for targeted thrombolytic therapy...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS applied materials & interfaces 2018-10, Vol.10 (39), p.32988-32997
Hauptverfasser:	Hu, Jiangnan, Huang, Shengwei, Zhu, Lu, Huang, Weijie, Zhao, Yiping, Jin, Kunlin, ZhuGe, Qichuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Fibrinolytic Agents - therapeutic use Ischemia - drug therapy Male Mice Microscopy, Electron, Scanning Transmission Stroke - drug therapy Thrombolytic Therapy - methods Tissue Plasminogen Activator - chemistry Tissue Plasminogen Activator - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!