Reduced expression of SIRT1 and SOD-1 and the correlation between these levels in various regions of the brains of patients with Alzheimer's disease

AimsThis study was designed to explore the expression and distribution of silent information regulator 1 (SIRT1) and superoxide dismutase 1 (SOD-1) in various regions of the brains of patients with Alzheimer's disease (AD), as well as to assess potential correlations between the levels of these...

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Veröffentlicht in:	Journal of clinical pathology 2018-12, Vol.71 (12), p.1090-1099
Hauptverfasser:	Cao, Kun, Dong, Yang-Ting, Xiang, Jie, Xu, Yi, Hong, Wei, Song, Hui, Guan, Zhi-Zhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aged, 80 and over Aging Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer's disease Apoptosis Brain Brain - metabolism Brain - pathology Case-Control Studies Dementia Diabetes Family medical history Female Fluorescent Antibody Technique Humans Immunoglobulins Immunohistochemistry Laboratories Male Neuropathology Oxidative Stress Pathology Peptides Proteins Sirtuin 1 - metabolism Superoxide Dismutase-1 - metabolism
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