Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management
Summary Overweight and obesity may carry a significant disease burden for patients with haemophilia (PWH), who experience reduced mobility due to joint inflammation, muscle dysfunction and haemophilic arthropathy. This review aimed to define the prevalence and clinical impact of overweight/obesity i...
Gespeichert in:
| Veröffentlicht in: | Obesity reviews 2018-11, Vol.19 (11), p.1569-1584 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1584 |
|---|---|
| container_issue | 11 |
| container_start_page | 1569 |
| container_title | Obesity reviews |
| container_volume | 19 |
| creator | Wilding, J. Zourikian, N. Di Minno, M. Khair, K. Marquardt, N. Benson, G. Ozelo, M. Hermans, C. |
| description | Summary
Overweight and obesity may carry a significant disease burden for patients with haemophilia (PWH), who experience reduced mobility due to joint inflammation, muscle dysfunction and haemophilic arthropathy. This review aimed to define the prevalence and clinical impact of overweight/obesity in the global population of PWH. A detailed literature search pertaining to overweight/obesity in haemophilia in the last 15 years (2003–2018) was conducted, followed by a meta‐analysis of epidemiological data. The estimated pooled prevalence of overweight/obesity in European and North American PWH was 31%. Excess weight in PWH is associated with a decreased range in motion of joints, accelerated loss of joint mobility and increase in chronic pain. Additionally, the cumulative disease burden of obesity and haemophilia may impact the requirement for joint surgery, occurrence of perioperative complications and the prevalence of anxiety and depression that associates with chronic illness. Best practice guidelines for obesity prevention and weight management, based on multidisciplinary expert perspectives, are considered for adult and paediatric PWH. Recommendations in the haemophilia context emphasize the importance of patient education and tailoring engagement in physical activity to avoid the risk of traumatic bleeding. |
| doi_str_mv | 10.1111/obr.12746 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2100328098</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2121170335</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3886-b432d630bf48e76b2e34c32b2694d2e1408754d6e33e4c94ab15276b94af6c693</originalsourceid><addsrcrecordid>eNp10c9LHDEUB_AgFbXqwX9AAr200NX82syMt3ZpVRAWpAVvQzLzZjeSSdJkptv974076qFgLnkkH7483kPojJILms-l1_GCskLIPXREhSxmRVk9fHirS3qIPqb0SAgtKk4P0CEntCwlJUcoLDUkM2yxcXhYA15Zr5XFawW9D2tjjcLBh9GqwXh3hUOEv8qCa-ArNn2wptl9JKxci-FfgDhgH4zbvXU-4g2Y1XrAvXJqBT244QTtd8omOH25j9Hvnz9-LW5md8vr28W3u1nDc2szLThrJSe6EyUUUjPgouFMM1mJlgEVpCzmopXAOYimEkrTOcsuV51sZMWP0ecpN0T_Z4Q01L1JDVirHPgx1YwSwllJqjLTT__RRz9Gl7vLilFaEM7nWX2ZVBN9ShG6OkTTq7itKamf11DnNdS7NWR7_pI46h7aN_k69wwuJ7AxFrbvJ9XL7_dT5BMVu5Hu</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2121170335</pqid></control><display><type>article</type><title>Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Wilding, J. ; Zourikian, N. ; Di Minno, M. ; Khair, K. ; Marquardt, N. ; Benson, G. ; Ozelo, M. ; Hermans, C.</creator><creatorcontrib>Wilding, J. ; Zourikian, N. ; Di Minno, M. ; Khair, K. ; Marquardt, N. ; Benson, G. ; Ozelo, M. ; Hermans, C.</creatorcontrib><description>Summary
Overweight and obesity may carry a significant disease burden for patients with haemophilia (PWH), who experience reduced mobility due to joint inflammation, muscle dysfunction and haemophilic arthropathy. This review aimed to define the prevalence and clinical impact of overweight/obesity in the global population of PWH. A detailed literature search pertaining to overweight/obesity in haemophilia in the last 15 years (2003–2018) was conducted, followed by a meta‐analysis of epidemiological data. The estimated pooled prevalence of overweight/obesity in European and North American PWH was 31%. Excess weight in PWH is associated with a decreased range in motion of joints, accelerated loss of joint mobility and increase in chronic pain. Additionally, the cumulative disease burden of obesity and haemophilia may impact the requirement for joint surgery, occurrence of perioperative complications and the prevalence of anxiety and depression that associates with chronic illness. Best practice guidelines for obesity prevention and weight management, based on multidisciplinary expert perspectives, are considered for adult and paediatric PWH. Recommendations in the haemophilia context emphasize the importance of patient education and tailoring engagement in physical activity to avoid the risk of traumatic bleeding.</description><identifier>ISSN: 1467-7881</identifier><identifier>EISSN: 1467-789X</identifier><identifier>DOI: 10.1111/obr.12746</identifier><identifier>PMID: 30188610</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Anxiety ; Best practice ; Bleeding ; Body weight ; Chronic pain ; Comorbidity ; Complications ; Data processing ; Disease control ; Epidemiology ; Haemophilia ; Hemophilia ; Hemophilia A - epidemiology ; Humans ; Joint diseases ; Joint surgery ; Mental depression ; Mobility ; Muscles ; Obesity ; Obesity - epidemiology ; Overweight ; Pain ; Physical activity ; Prevalence ; Surgery ; Weight control ; weight management ; Weight Reduction Programs</subject><ispartof>Obesity reviews, 2018-11, Vol.19 (11), p.1569-1584</ispartof><rights>2018 The Authors. published by John Wiley & Sons Ltd on behalf of World Obesity Federation</rights><rights>2018 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.</rights><rights>2018 World Obesity Federation</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3886-b432d630bf48e76b2e34c32b2694d2e1408754d6e33e4c94ab15276b94af6c693</citedby><cites>FETCH-LOGICAL-c3886-b432d630bf48e76b2e34c32b2694d2e1408754d6e33e4c94ab15276b94af6c693</cites><orcidid>0000-0003-2839-8404</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fobr.12746$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fobr.12746$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30188610$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wilding, J.</creatorcontrib><creatorcontrib>Zourikian, N.</creatorcontrib><creatorcontrib>Di Minno, M.</creatorcontrib><creatorcontrib>Khair, K.</creatorcontrib><creatorcontrib>Marquardt, N.</creatorcontrib><creatorcontrib>Benson, G.</creatorcontrib><creatorcontrib>Ozelo, M.</creatorcontrib><creatorcontrib>Hermans, C.</creatorcontrib><title>Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management</title><title>Obesity reviews</title><addtitle>Obes Rev</addtitle><description>Summary
Overweight and obesity may carry a significant disease burden for patients with haemophilia (PWH), who experience reduced mobility due to joint inflammation, muscle dysfunction and haemophilic arthropathy. This review aimed to define the prevalence and clinical impact of overweight/obesity in the global population of PWH. A detailed literature search pertaining to overweight/obesity in haemophilia in the last 15 years (2003–2018) was conducted, followed by a meta‐analysis of epidemiological data. The estimated pooled prevalence of overweight/obesity in European and North American PWH was 31%. Excess weight in PWH is associated with a decreased range in motion of joints, accelerated loss of joint mobility and increase in chronic pain. Additionally, the cumulative disease burden of obesity and haemophilia may impact the requirement for joint surgery, occurrence of perioperative complications and the prevalence of anxiety and depression that associates with chronic illness. Best practice guidelines for obesity prevention and weight management, based on multidisciplinary expert perspectives, are considered for adult and paediatric PWH. Recommendations in the haemophilia context emphasize the importance of patient education and tailoring engagement in physical activity to avoid the risk of traumatic bleeding.</description><subject>Anxiety</subject><subject>Best practice</subject><subject>Bleeding</subject><subject>Body weight</subject><subject>Chronic pain</subject><subject>Comorbidity</subject><subject>Complications</subject><subject>Data processing</subject><subject>Disease control</subject><subject>Epidemiology</subject><subject>Haemophilia</subject><subject>Hemophilia</subject><subject>Hemophilia A - epidemiology</subject><subject>Humans</subject><subject>Joint diseases</subject><subject>Joint surgery</subject><subject>Mental depression</subject><subject>Mobility</subject><subject>Muscles</subject><subject>Obesity</subject><subject>Obesity - epidemiology</subject><subject>Overweight</subject><subject>Pain</subject><subject>Physical activity</subject><subject>Prevalence</subject><subject>Surgery</subject><subject>Weight control</subject><subject>weight management</subject><subject>Weight Reduction Programs</subject><issn>1467-7881</issn><issn>1467-789X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><recordid>eNp10c9LHDEUB_AgFbXqwX9AAr200NX82syMt3ZpVRAWpAVvQzLzZjeSSdJkptv974076qFgLnkkH7483kPojJILms-l1_GCskLIPXREhSxmRVk9fHirS3qIPqb0SAgtKk4P0CEntCwlJUcoLDUkM2yxcXhYA15Zr5XFawW9D2tjjcLBh9GqwXh3hUOEv8qCa-ArNn2wptl9JKxci-FfgDhgH4zbvXU-4g2Y1XrAvXJqBT244QTtd8omOH25j9Hvnz9-LW5md8vr28W3u1nDc2szLThrJSe6EyUUUjPgouFMM1mJlgEVpCzmopXAOYimEkrTOcsuV51sZMWP0ecpN0T_Z4Q01L1JDVirHPgx1YwSwllJqjLTT__RRz9Gl7vLilFaEM7nWX2ZVBN9ShG6OkTTq7itKamf11DnNdS7NWR7_pI46h7aN_k69wwuJ7AxFrbvJ9XL7_dT5BMVu5Hu</recordid><startdate>201811</startdate><enddate>201811</enddate><creator>Wilding, J.</creator><creator>Zourikian, N.</creator><creator>Di Minno, M.</creator><creator>Khair, K.</creator><creator>Marquardt, N.</creator><creator>Benson, G.</creator><creator>Ozelo, M.</creator><creator>Hermans, C.</creator><general>Wiley Subscription Services, Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7TS</scope><scope>C1K</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2839-8404</orcidid></search><sort><creationdate>201811</creationdate><title>Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management</title><author>Wilding, J. ; Zourikian, N. ; Di Minno, M. ; Khair, K. ; Marquardt, N. ; Benson, G. ; Ozelo, M. ; Hermans, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3886-b432d630bf48e76b2e34c32b2694d2e1408754d6e33e4c94ab15276b94af6c693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Anxiety</topic><topic>Best practice</topic><topic>Bleeding</topic><topic>Body weight</topic><topic>Chronic pain</topic><topic>Comorbidity</topic><topic>Complications</topic><topic>Data processing</topic><topic>Disease control</topic><topic>Epidemiology</topic><topic>Haemophilia</topic><topic>Hemophilia</topic><topic>Hemophilia A - epidemiology</topic><topic>Humans</topic><topic>Joint diseases</topic><topic>Joint surgery</topic><topic>Mental depression</topic><topic>Mobility</topic><topic>Muscles</topic><topic>Obesity</topic><topic>Obesity - epidemiology</topic><topic>Overweight</topic><topic>Pain</topic><topic>Physical activity</topic><topic>Prevalence</topic><topic>Surgery</topic><topic>Weight control</topic><topic>weight management</topic><topic>Weight Reduction Programs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilding, J.</creatorcontrib><creatorcontrib>Zourikian, N.</creatorcontrib><creatorcontrib>Di Minno, M.</creatorcontrib><creatorcontrib>Khair, K.</creatorcontrib><creatorcontrib>Marquardt, N.</creatorcontrib><creatorcontrib>Benson, G.</creatorcontrib><creatorcontrib>Ozelo, M.</creatorcontrib><creatorcontrib>Hermans, C.</creatorcontrib><collection>Wiley Online Library (Open Access Collection)</collection><collection>Wiley Online Library (Open Access Collection)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Physical Education Index</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Obesity reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilding, J.</au><au>Zourikian, N.</au><au>Di Minno, M.</au><au>Khair, K.</au><au>Marquardt, N.</au><au>Benson, G.</au><au>Ozelo, M.</au><au>Hermans, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management</atitle><jtitle>Obesity reviews</jtitle><addtitle>Obes Rev</addtitle><date>2018-11</date><risdate>2018</risdate><volume>19</volume><issue>11</issue><spage>1569</spage><epage>1584</epage><pages>1569-1584</pages><issn>1467-7881</issn><eissn>1467-789X</eissn><abstract>Summary
Overweight and obesity may carry a significant disease burden for patients with haemophilia (PWH), who experience reduced mobility due to joint inflammation, muscle dysfunction and haemophilic arthropathy. This review aimed to define the prevalence and clinical impact of overweight/obesity in the global population of PWH. A detailed literature search pertaining to overweight/obesity in haemophilia in the last 15 years (2003–2018) was conducted, followed by a meta‐analysis of epidemiological data. The estimated pooled prevalence of overweight/obesity in European and North American PWH was 31%. Excess weight in PWH is associated with a decreased range in motion of joints, accelerated loss of joint mobility and increase in chronic pain. Additionally, the cumulative disease burden of obesity and haemophilia may impact the requirement for joint surgery, occurrence of perioperative complications and the prevalence of anxiety and depression that associates with chronic illness. Best practice guidelines for obesity prevention and weight management, based on multidisciplinary expert perspectives, are considered for adult and paediatric PWH. Recommendations in the haemophilia context emphasize the importance of patient education and tailoring engagement in physical activity to avoid the risk of traumatic bleeding.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30188610</pmid><doi>10.1111/obr.12746</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0003-2839-8404</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1467-7881 |
| ispartof | Obesity reviews, 2018-11, Vol.19 (11), p.1569-1584 |
| issn | 1467-7881 1467-789X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2100328098 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Anxiety Best practice Bleeding Body weight Chronic pain Comorbidity Complications Data processing Disease control Epidemiology Haemophilia Hemophilia Hemophilia A - epidemiology Humans Joint diseases Joint surgery Mental depression Mobility Muscles Obesity Obesity - epidemiology Overweight Pain Physical activity Prevalence Surgery Weight control weight management Weight Reduction Programs |
| title | Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T14%3A38%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Obesity%20in%20the%20global%20haemophilia%20population:%20prevalence,%20implications%20and%20expert%20opinions%20for%20weight%20management&rft.jtitle=Obesity%20reviews&rft.au=Wilding,%20J.&rft.date=2018-11&rft.volume=19&rft.issue=11&rft.spage=1569&rft.epage=1584&rft.pages=1569-1584&rft.issn=1467-7881&rft.eissn=1467-789X&rft_id=info:doi/10.1111/obr.12746&rft_dat=%3Cproquest_cross%3E2121170335%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2121170335&rft_id=info:pmid/30188610&rfr_iscdi=true |