Membranotropic effects of ω-hydroxypalmitic acid and Ca2+ on rat liver mitochondria and lecithin liposomes. Aggregation and membrane permeabilization

The paper examines membranotropic Ca 2+ -dependent effects of ω-hydroxypalmitic acid (HPA), a product of ω-oxidation of fatty acids, on the isolated rat liver mitochondria and artificial membrane systems (liposomes). It was established that in the presence of Ca 2+ , HPA induced aggregation of liver...

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Veröffentlicht in:	Journal of bioenergetics and biomembranes 2018-10, Vol.50 (5), p.391-401
Hauptverfasser:	Dubinin, Mikhail V., Samartsev, Victor N., Stepanova, Anastasia E., Khoroshavina, Ekaterina I., Penkov, Nikita V., Yashin, Valery A., Starinets, Vlada S., Mikheeva, Irina B., Gudkov, Sergey V., Belosludtsev, Konstantin N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration Animal Anatomy Animal Biochemistry Biochemistry Bioorganic Chemistry Calcium (mitochondrial) Calcium ions Chemistry Chemistry and Materials Science Cytochrome c Cytochromes Fatty acids Fluorescence Fluorescent dyes Fluorescent indicators Histology Inhibitors Lecithin Liposomes Liver Lysis Magnesium Membrane potential Membranes Mitochondria Mitochondrial DNA Morphology NAD Organelles Organic Chemistry Oxidation Ruthenium Ruthenium red Sulforhodamine
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