Direct and Regioselective C–H Oxidative Difluoromethylation of Heteroarenes

The difluoromethyl group (CF2H) is of great interest in the area of medicinal chemistry. However, the investigation of molecular scaffolds containing this group has been hampered by the limitation of synthetic methods for the introduction of CF2H into heteroarenes. Herein we disclose a new strategy...

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Veröffentlicht in:	Journal of the American Chemical Society 2018-09, Vol.140 (37), p.11613-11617
Hauptverfasser:	Zhu, Sheng-Qing, Liu, Yin-Li, Li, Huan, Xu, Xiu-Hua, Qing, Feng-Ling
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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