Clinical and Radiographic Predictors of Great Vessel Resection or Reconstruction During Retroperitoneal Lymph Node Dissection for Testicular Cancer

Clinical and Radiographic Predictors of Great Vessel Resection or Reconstruction During Retroperitoneal Lymph Node Dissection for Testicular Cancer

To evaluate whether specific clinical or radiographic factors predict inferior vena cava (IVC) or abdominal aortic (AA) resection or reconstruction (RoR) at the time of postchemotherapy retroperitoneal lymph node dissection (RPLND) for germ cell tumors of the testicle. Two hundred seventy-seven pati...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 2019-01, Vol.123, p.186-190
Hauptverfasser: Johnson, Scott C., Smith, Zachary L., Nottingham, Charles, Schwen, Zeyad R., Thomas, Stephen, Fishman, Elliot K., Lee, Nam Ju, Pierorazio, Philip M., Eggener, Scott E.
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container_start_page 186
container_title Urology (Ridgewood, N.J.)
container_volume 123
creator Johnson, Scott C.
Smith, Zachary L.
Nottingham, Charles
Schwen, Zeyad R.
Thomas, Stephen
Fishman, Elliot K.
Lee, Nam Ju
Pierorazio, Philip M.
Eggener, Scott E.
description To evaluate whether specific clinical or radiographic factors predict inferior vena cava (IVC) or abdominal aortic (AA) resection or reconstruction (RoR) at the time of postchemotherapy retroperitoneal lymph node dissection (RPLND) for germ cell tumors of the testicle. Two hundred seventy-seven patients undergoing postchemotherapy RPLND at two institutions between 2005 and 2015 were identified. Preoperative imaging was reviewed with radiologists blinded to operative details. Univariable and multivariable logistic regressions were performed, and a model was created to predict the need for great vessel RoR using radiographic and clinical factors. Of 97 patients with preoperative imaging and clinical data available, 16 (17%) underwent RoR at RPLND. On univariable analysis dominant mass size, degree of circumferential vessel involvement, and vessel deformity were associated with RoR (all P 135° (odds ratio 65.5, 7.8-548, P 330° (odds ratio 29.0, 3.44-245, P
doi_str_mv 10.1016/j.urology.2018.08.028
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These thresholds yielded a PPV of 48% and 50% and a NPV of 92% and 97% for IVC and AA RoR, respectively. Degree of circumferential involvement of the great vessels is an independent predictor for resection or reconstruction of the IVC or AA at postchemotherapy RPLND. Patients at high risk of great vessel reconstruction should be informed accordingly and have the proper teams available for complex vascular reconstruction.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2018.08.028</identifier><identifier>PMID: 30179635</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><ispartof>Urology (Ridgewood, N.J.), 2019-01, Vol.123, p.186-190</ispartof><rights>2018</rights><rights>Copyright © 2018. 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