Effects of age on the pharmacokinetics of single dose sulfamethazine after intravenous administration in cattle

Sulphonamides are still being used widely, influenced by the low cost and the efficacy against many common bacterial infections, since they present a broad spectrum of activity. The aim of this study was to determine the effect of age on the pharmacokinetic/pharmacodynamics (PK/PD) integration of in...

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Veröffentlicht in:	Veterinary research communications 2008-10, Vol.32 (7), p.509-519
Hauptverfasser:	Baroni, Eduardo E, Díaz, Diego C, Picco, Eduardo, Waxman, Samanta, Rodríguez, Casilda, San Andrés, Manuel I, Boggio, Juan C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology animal age Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - blood Anti-Bacterial Agents - pharmacokinetics Area Under Curve Biomedical and Life Sciences blood chemistry calves Cattle dosage dose response Dose-Response Relationship, Drug Female Half-Life Holstein Injections, Intravenous intravenous injection Life Sciences Microbial Sensitivity Tests Original Article pharmacokinetics sulfamethazine Sulfamethazine - administration & dosage Sulfamethazine - blood Sulfamethazine - pharmacokinetics sulfonamides temporal variation Veterinary Medicine/Veterinary Science Zoology
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