Mesenchymal stem cells attenuate sepsis-induced liver injury via inhibiting M1 polarization of Kupffer cells

Sepsis is a leading cause of death in intensive care units that can result in acute hepatic damage. Animal experiments and clinical trials have shown that mesenchymal stem cell (MSC) therapy has some beneficial in several liver diseases. However, the protective effects of MSC therapy on sepsis-induc...

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Veröffentlicht in:	Molecular and cellular biochemistry 2019-02, Vol.452 (1-2), p.187-197
Hauptverfasser:	Liang, Xujing, Li, Taoyuan, Zhou, Qiuchan, Pi, Sainan, Li, Yadan, Chen, Xiaojia, Weng, Zeping, Li, Hongmei, Zhao, Ying, Wang, Huadong, Chen, Youpeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Alanine transaminase Animal experimentation Animal research Aspartate Aspartate transaminase Attenuation Bile Biochemistry Biomedical and Life Sciences Cardiology Cecum Clinical trials Cytokines Death Hepatocytes Hospitals Infection Inflammation Injuries Intensive care units Interleukin 10 Interleukin 4 Interleukin 6 Kupffer cells Life Sciences Lipopolysaccharides Liver Liver diseases Lymphocytes B Medical Biochemistry Medical research Medical schools Mesenchymal stem cells Mesenchyme Mitogens NF-κB protein Nuclear transport Oncology Phenotypes Polarization Rats Rodents Sepsis Stem cell transplantation Stem cells Therapy Transaminase Translocation
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