Synthesis of polycyclic spirooxindoles via an asymmetric catalytic one-pot stepwise Aldol/chloroetherification/aromatization procedure

A general method for the synthesis of chiral pentacyclic spirooxindoles containing a tetrahydropyrano[2,3-b]indole scaffold through a one-pot stepwise sequence from 3-(3-indolomethyl)oxindole, paraformaldehyde and NCS is reported. Furthermore, the pentacyclic spirooxindoles could be transformed to b...

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Veröffentlicht in:	Organic & biomolecular chemistry 2018, Vol.16 (36), p.6647-6651
Hauptverfasser:	Jiang, Yan, Yu, Shuo-Wen, Yang, Yi, Liu, Ying-Le, Xu, Xiao-Ying, Zhang, Xiao-Mei, Yuan, Wei-Cheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Catalysis Chemical synthesis Crystallography Indoles
Online-Zugang:	Volltext
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