Designer probiotic Lactobacillus plantarum expressing oxalate decarboxylase developed using group II intron degrades intestinal oxalate in hyperoxaluric rats

Increased intestinal absorption of oxalate causes hyperoxaluria, a major risk factor for kidney stone disease. Intestinal colonization of recombinant probiotic bacteria expressing oxalate-degrading gene (OxdC) is an effective therapeutic option for recurrent calcium oxalate (CaOx) stone disease. The...

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Veröffentlicht in:	Microbiological research 2018-10, Vol.215, p.65-75
Hauptverfasser:	Paul, Eldho, Albert, Abhishek, Ponnusamy, Sasikumar, Mishra, Srishti Rajkumar, Vignesh, Amalraj Ganesh, Sivakumar, Selvi Mariaraj, Sivasamy, Gomathi, Sadasivam, Selvam Govindan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine racemase Group II intron Hyperoxaluria Lactobacillus plantarum Oxalate decarboxylase Potassium oxalate
Online-Zugang:	Volltext
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