Discovery and preclinical validation of proteomic biomarkers in saliva for early detection of oral squamous cell carcinomas

Objectives Our aim was to identify and prevalidate a set of salivary proteins that can distinguish oral squamous cell carcinomas (OSCC) patients from healthy individuals and patients with oral potentially malignant disorders (OPMD). Subjects and methods Proteomes of 60 saliva samples from healthy in...

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Veröffentlicht in:	Oral diseases 2019-01, Vol.25 (1), p.97-107
Hauptverfasser:	Shan, Jing, Sun, Zhida, Yang, Jingjing, Xu, Juanyong, Shi, Wei, Wu, You, Fan, Yuan, Li, Huaiqi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers Biomarkers, Tumor - analysis Calcium-binding protein Carcinoma, Squamous Cell - diagnosis Dentistry Early Detection of Cancer Enzyme-linked immunosorbent assay Female Humans Interleukin 1 Male Middle Aged Mouth Neoplasms - diagnosis Oral cancer Oral carcinoma oral potentially malignant disorders Oral squamous cell carcinoma Proteins Proteomics Quantitation Saliva Saliva - chemistry saliva proteomics Sensitivity and Specificity Squamous cell carcinoma
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