Prevention of Kainic Acid-induced Limbic Seizures and Fos Expression by the GABA-A Receptor Agonist Muscimol

Fos oncoprotein expression has been shown to be a sensitive marker for sequential neuronal activation in response to a specific stimulus. The present study investigated the effect of the γ‐aminobutyric acid (GABA)‐A receptor agonist muscimol on kainic acid (KA)‐induced limbic seizures and Fos expres...

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Veröffentlicht in:	The European journal of neuroscience 1997-01, Vol.9 (1), p.29-40
Hauptverfasser:	Zhang, Xia, Le Gal La Salle, Gildas, Ridoux, Valerie, Yu, Peter H., Ju, Gong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Brain Chemistry - drug effects c-fos gene Epilepsy, Temporal Lobe - chemically induced Epilepsy, Temporal Lobe - prevention & control Excitatory Amino Acid Agonists - toxicity GABA Agonists - pharmacology GABA-A Receptor Agonists Immunohistochemistry Kainic Acid - antagonists & inhibitors Kainic Acid - toxicity Limbic System - anatomy & histology Limbic System - drug effects Male Muscimol - pharmacology Proto-Oncogene Proteins c-fos - biosynthesis rat brain Rats Rats, Sprague-Dawley temporal lobe epilepsy
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