High expression of miR‐510 was associated with CGG expansion located at upstream of FMR1 into full mutation

MicroRNAs (miRNAs) have been found to play an important role in the regulation of gene expression in eukaryotic organisms at the posttranscriptional level. More than half of miRNA genes have been recognized to be located in different fragile sites. Among them, miR‐510 was located on chromosome X in...

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Veröffentlicht in:	Journal of cellular biochemistry 2019-02, Vol.120 (2), p.1916-1923
Hauptverfasser:	Fazeli, Zahra, Ghaderian, Sayyed Mohammad Hossein, Najmabadi, Hossein, Omrani, Mir Davood
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics CGG expansion DNA methylation Expansion FMR1 full mutation female carrier FMR1 protein Fragile sites fragile X (Cap X) syndrome (FXS) Fragile X syndrome Gene expression Genes Intellectual disabilities Mesenchyme miRNA miR‐510 Mutation Nervous system Peripheral blood Polymerase chain reaction Post-transcription Ribonucleic acid RNA Stem cells VHL protein
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