Scopolamine Use in the Perioperative Patient: A Systematic Review

Abstract Scopolamine is an antiemetic agent used for postoperative nausea and vomiting prevention; however, it has anticholinergic effects (eg, bradycardia, dry mouth, dizziness, visual disturbances). Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to...

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Veröffentlicht in:AORN journal 2018-09, Vol.108 (3), p.287-295
Hauptverfasser: Kassel, Lynn, PharmD, BCPS, Nelson, Megan, PharmD, MBA, Shine, Jaclyn, PharmD, MBA, Jones, Laura R., BSN, BS, RN, Kassel, Cale, MD
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container_start_page 287
container_title AORN journal
container_volume 108
creator Kassel, Lynn, PharmD, BCPS
Nelson, Megan, PharmD, MBA
Shine, Jaclyn, PharmD, MBA
Jones, Laura R., BSN, BS, RN
Kassel, Cale, MD
description Abstract Scopolamine is an antiemetic agent used for postoperative nausea and vomiting prevention; however, it has anticholinergic effects (eg, bradycardia, dry mouth, dizziness, visual disturbances). Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to patients. This systematic review describes the anticholinergic effects of scopolamine in perioperative patient populations. After searching the available literature, we reviewed the eligible articles to determine whether they met the inclusion criteria (eg, full text, English language, included a discussion of scopolamine's anticholinergic effects in perioperative patients). Twenty-six articles were included in this review. We used The Johns Hopkins Research Evidence Appraisal Tool to appraise the literature. The results of this literature review reveal that clinicians should avoid administering scopolamine to certain perioperative patient populations (ie, pediatric, older adult).
doi_str_mv 10.1002/aorn.12336
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Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to patients. This systematic review describes the anticholinergic effects of scopolamine in perioperative patient populations. After searching the available literature, we reviewed the eligible articles to determine whether they met the inclusion criteria (eg, full text, English language, included a discussion of scopolamine's anticholinergic effects in perioperative patients). Twenty-six articles were included in this review. We used The Johns Hopkins Research Evidence Appraisal Tool to appraise the literature. 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subjects adverse drug effects
Anesthesia
anticholinergic effects
Cardiac arrhythmia
Drug therapy
Evidence-based medicine
Histamine
Laparoscopy
Medical/Surgical
Nausea
Nursing
Patients
Pediatrics
postoperative nausea and vomiting
Prevention
scopolamine
Side effects
Surgery
Systematic review
Vomiting
title Scopolamine Use in the Perioperative Patient: A Systematic Review
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