Scopolamine Use in the Perioperative Patient: A Systematic Review
Abstract Scopolamine is an antiemetic agent used for postoperative nausea and vomiting prevention; however, it has anticholinergic effects (eg, bradycardia, dry mouth, dizziness, visual disturbances). Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to...
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Veröffentlicht in: | AORN journal 2018-09, Vol.108 (3), p.287-295 |
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creator | Kassel, Lynn, PharmD, BCPS Nelson, Megan, PharmD, MBA Shine, Jaclyn, PharmD, MBA Jones, Laura R., BSN, BS, RN Kassel, Cale, MD |
description | Abstract Scopolamine is an antiemetic agent used for postoperative nausea and vomiting prevention; however, it has anticholinergic effects (eg, bradycardia, dry mouth, dizziness, visual disturbances). Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to patients. This systematic review describes the anticholinergic effects of scopolamine in perioperative patient populations. After searching the available literature, we reviewed the eligible articles to determine whether they met the inclusion criteria (eg, full text, English language, included a discussion of scopolamine's anticholinergic effects in perioperative patients). Twenty-six articles were included in this review. We used The Johns Hopkins Research Evidence Appraisal Tool to appraise the literature. The results of this literature review reveal that clinicians should avoid administering scopolamine to certain perioperative patient populations (ie, pediatric, older adult). |
doi_str_mv | 10.1002/aorn.12336 |
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Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to patients. This systematic review describes the anticholinergic effects of scopolamine in perioperative patient populations. After searching the available literature, we reviewed the eligible articles to determine whether they met the inclusion criteria (eg, full text, English language, included a discussion of scopolamine's anticholinergic effects in perioperative patients). Twenty-six articles were included in this review. We used The Johns Hopkins Research Evidence Appraisal Tool to appraise the literature. The results of this literature review reveal that clinicians should avoid administering scopolamine to certain perioperative patient populations (ie, pediatric, older adult).</description><identifier>ISSN: 1878-0369</identifier><identifier>ISSN: 0001-2092</identifier><identifier>EISSN: 1878-0369</identifier><identifier>DOI: 10.1002/aorn.12336</identifier><identifier>PMID: 30156728</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>adverse drug effects ; Anesthesia ; anticholinergic effects ; Cardiac arrhythmia ; Drug therapy ; Evidence-based medicine ; Histamine ; Laparoscopy ; Medical/Surgical ; Nausea ; Nursing ; Patients ; Pediatrics ; postoperative nausea and vomiting ; Prevention ; scopolamine ; Side effects ; Surgery ; Systematic review ; Vomiting</subject><ispartof>AORN journal, 2018-09, Vol.108 (3), p.287-295</ispartof><rights>AORN, Inc.</rights><rights>AORN, Inc, 2018</rights><rights>AORN, Inc, 2018.</rights><rights>Copyright John Wiley & Sons, Inc. Sep 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4126-8a5f67d0a925fe1b8082191d04b14fc09ace737aeae17a1f624fade65c8a85333</citedby><cites>FETCH-LOGICAL-c4126-8a5f67d0a925fe1b8082191d04b14fc09ace737aeae17a1f624fade65c8a85333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Faorn.12336$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Faorn.12336$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27922,27923,45572,45573</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30156728$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kassel, Lynn, PharmD, BCPS</creatorcontrib><creatorcontrib>Nelson, Megan, PharmD, MBA</creatorcontrib><creatorcontrib>Shine, Jaclyn, PharmD, MBA</creatorcontrib><creatorcontrib>Jones, Laura R., BSN, BS, RN</creatorcontrib><creatorcontrib>Kassel, Cale, MD</creatorcontrib><title>Scopolamine Use in the Perioperative Patient: A Systematic Review</title><title>AORN journal</title><addtitle>AORN J</addtitle><description>Abstract Scopolamine is an antiemetic agent used for postoperative nausea and vomiting prevention; however, it has anticholinergic effects (eg, bradycardia, dry mouth, dizziness, visual disturbances). Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to patients. This systematic review describes the anticholinergic effects of scopolamine in perioperative patient populations. After searching the available literature, we reviewed the eligible articles to determine whether they met the inclusion criteria (eg, full text, English language, included a discussion of scopolamine's anticholinergic effects in perioperative patients). Twenty-six articles were included in this review. We used The Johns Hopkins Research Evidence Appraisal Tool to appraise the literature. The results of this literature review reveal that clinicians should avoid administering scopolamine to certain perioperative patient populations (ie, pediatric, older adult).</description><subject>adverse drug effects</subject><subject>Anesthesia</subject><subject>anticholinergic effects</subject><subject>Cardiac arrhythmia</subject><subject>Drug therapy</subject><subject>Evidence-based medicine</subject><subject>Histamine</subject><subject>Laparoscopy</subject><subject>Medical/Surgical</subject><subject>Nausea</subject><subject>Nursing</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>postoperative nausea and vomiting</subject><subject>Prevention</subject><subject>scopolamine</subject><subject>Side effects</subject><subject>Surgery</subject><subject>Systematic review</subject><subject>Vomiting</subject><issn>1878-0369</issn><issn>0001-2092</issn><issn>1878-0369</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kctKAzEUhoMoWi8bH0AG3IhQzUnmknEh1OINikpr1yFNz2B0LjWZtvRtfBafzIy1RVyYzUnClz-H7xByCPQMKGXnqrLlGTDO4w3SApGINuVxuvlrv0N2nXulfnEWbZMdTiGKEyZa5Gqgq0mVq8KUGAwdBqYM6hcMntCaaoJW1WbmT75gWV8Enc-PwcLVWPgLHfRxZnC-T7YylTs8-Kl7ZHhz_dy9a_ceb--7nV5bh8DitlBRFidjqlIWZQgjQQWDFMY0HEGYaZoqjQlPFCqEREEWszBTY4wjLZSIOOd75GSZO7HV-xRdLQvjNOa5KrGaOsloGkdRKpLUo8d_0NdqakvfnWTAIRH-44Y6XVLaVs5ZzOTEmkLZhQQqG7OyMSu_zXr46CdyOipwvEZXKj0AS2Buclz8EyU7j_2HVejl8g16b96llTo3pdEqf8MFunXTIB2TVA6agTbzBMFpSNOQfwFPfpeP</recordid><startdate>201809</startdate><enddate>201809</enddate><creator>Kassel, Lynn, PharmD, BCPS</creator><creator>Nelson, Megan, PharmD, MBA</creator><creator>Shine, Jaclyn, PharmD, MBA</creator><creator>Jones, Laura R., BSN, BS, RN</creator><creator>Kassel, Cale, MD</creator><general>John Wiley & Sons, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>201809</creationdate><title>Scopolamine Use in the Perioperative Patient: A Systematic Review</title><author>Kassel, Lynn, PharmD, BCPS ; 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however, it has anticholinergic effects (eg, bradycardia, dry mouth, dizziness, visual disturbances). Avoiding scopolamine use in specific populations is crucial to prevent adverse effects and harm to patients. This systematic review describes the anticholinergic effects of scopolamine in perioperative patient populations. After searching the available literature, we reviewed the eligible articles to determine whether they met the inclusion criteria (eg, full text, English language, included a discussion of scopolamine's anticholinergic effects in perioperative patients). Twenty-six articles were included in this review. We used The Johns Hopkins Research Evidence Appraisal Tool to appraise the literature. The results of this literature review reveal that clinicians should avoid administering scopolamine to certain perioperative patient populations (ie, pediatric, older adult).</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>30156728</pmid><doi>10.1002/aorn.12336</doi><tpages>9</tpages></addata></record> |
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subjects | adverse drug effects Anesthesia anticholinergic effects Cardiac arrhythmia Drug therapy Evidence-based medicine Histamine Laparoscopy Medical/Surgical Nausea Nursing Patients Pediatrics postoperative nausea and vomiting Prevention scopolamine Side effects Surgery Systematic review Vomiting |
title | Scopolamine Use in the Perioperative Patient: A Systematic Review |
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