The role of TCF3 as potential master regulator in blastemal Wilms tumors

Wilms tumors are the most common type of pediatric kidney tumors. While the overall prognosis for patients is favorable, especially tumors that exhibit a blastemal subtype after preoperative chemotherapy have a poor prognosis. For an improved risk assessment and therapy stratification, it is essenti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of cancer 2019-03, Vol.144 (6), p.1432-1443
Hauptverfasser:	Kehl, Tim, Schneider, Lara, Kattler, Kathrin, Stöckel, Daniel, Wegert, Jenny, Gerstner, Nico, Ludwig, Nicole, Distler, Ute, Tenzer, Stefan, Gessler, Manfred, Walter, Jörn, Keller, Andreas, Graf, Norbert, Meese, Eckart, Lenhof, Hans‐Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Antineoplastic Combined Chemotherapy Protocols - therapeutic use Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Biomarkers Biopsy blastemal subtype Cancer Chemoresistance Chemotherapy Child Child, Preschool Chromatin remodeling Datasets as Topic Embryo cells Embryogenesis Embryonic growth stage Female Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Infant Kidney - cytology Kidney - pathology Kidney - surgery Kidney Neoplasms - genetics Kidney Neoplasms - pathology Kidney Neoplasms - therapy Kidneys Male Malignancy Medical research Mice Molecular modelling Neoadjuvant Therapy - methods Neoplastic Stem Cells - pathology Nephrectomy Primary Cell Culture Prognosis REGGAE Risk assessment SIOP Stem cell transplantation Stem cells TCF3 transcriptional regulators Tumor Cells, Cultured Tumors Wilms tumor Wilms Tumor - genetics Wilms Tumor - pathology Wilms Tumor - therapy Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!