Strategies to maximize influenza vaccine impact in older adults
Older adults are disproportionately affected by influenza morbidity and mortality. In most high income countries, influenza vaccine policies target persons age ≥65 years for influenza vaccination. Many low-resource settings do not utilize seasonal influenza vaccination. Barriers to influenza prevent...
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| Veröffentlicht in: | Vaccine 2018-09, Vol.36 (40), p.5940-5948 |
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| creator | Whitaker, Jennifer A. von Itzstein, Mitchell S. Poland, Gregory A. |
| description | Older adults are disproportionately affected by influenza morbidity and mortality. In most high income countries, influenza vaccine policies target persons age ≥65 years for influenza vaccination. Many low-resource settings do not utilize seasonal influenza vaccination. Barriers to influenza prevention among older adults around the globe are multiple and some vary between high- and low-resource settings. To maximize influenza prevention in the older adult population, gaps in influenza vaccination coverage and improvements in vaccine efficacy are needed. The focus of this article is on the data for currently available vaccine strategies to maximize influenza vaccine impact, with a focus on high-resource settings. We also discuss novel influenza vaccine strategies needed for older adults worldwide. |
| doi_str_mv | 10.1016/j.vaccine.2018.08.040 |
| format | Article |
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In most high income countries, influenza vaccine policies target persons age ≥65 years for influenza vaccination. Many low-resource settings do not utilize seasonal influenza vaccination. Barriers to influenza prevention among older adults around the globe are multiple and some vary between high- and low-resource settings. To maximize influenza prevention in the older adult population, gaps in influenza vaccination coverage and improvements in vaccine efficacy are needed. The focus of this article is on the data for currently available vaccine strategies to maximize influenza vaccine impact, with a focus on high-resource settings. We also discuss novel influenza vaccine strategies needed for older adults worldwide.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2018.08.040</identifier><identifier>PMID: 30153995</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adjuvants ; Adjuvants, Immunologic - administration & dosage ; Adult ; Adults ; Age ; Age Factors ; Aged ; Aged, 80 and over ; Global Health ; Health Resources ; Hospitalization ; Humans ; Illnesses ; Immunocompromised Host ; Immunologic ; Infections ; Influenza ; Influenza vaccines ; Influenza Vaccines - therapeutic use ; Influenza, Human ; Influenza, Human - epidemiology ; Influenza, Human - prevention & control ; Medical laboratories ; Morbidity ; Mortality ; Older people ; Pneumonia ; Population ; Prevention ; Public health ; Seasons ; Systematic review ; Vaccination ; Vaccination - economics ; Vaccination - legislation & jurisprudence ; Vaccination Coverage - statistics & numerical data ; Vaccine efficacy ; Vaccines ; Working groups</subject><ispartof>Vaccine, 2018-09, Vol.36 (40), p.5940-5948</ispartof><rights>2018 Elsevier Ltd</rights><rights>Copyright © 2018 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Sep 25, 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-86bed627851ed8aed5ce9d89951afd6e18816a0ca03c08c2e5b159556bac53e43</citedby><cites>FETCH-LOGICAL-c393t-86bed627851ed8aed5ce9d89951afd6e18816a0ca03c08c2e5b159556bac53e43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0264410X18311691$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27902,27903,65308</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30153995$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Whitaker, Jennifer A.</creatorcontrib><creatorcontrib>von Itzstein, Mitchell S.</creatorcontrib><creatorcontrib>Poland, Gregory A.</creatorcontrib><title>Strategies to maximize influenza vaccine impact in older adults</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Older adults are disproportionately affected by influenza morbidity and mortality. In most high income countries, influenza vaccine policies target persons age ≥65 years for influenza vaccination. Many low-resource settings do not utilize seasonal influenza vaccination. Barriers to influenza prevention among older adults around the globe are multiple and some vary between high- and low-resource settings. To maximize influenza prevention in the older adult population, gaps in influenza vaccination coverage and improvements in vaccine efficacy are needed. The focus of this article is on the data for currently available vaccine strategies to maximize influenza vaccine impact, with a focus on high-resource settings. We also discuss novel influenza vaccine strategies needed for older adults worldwide.</description><subject>Adjuvants</subject><subject>Adjuvants, Immunologic - administration & dosage</subject><subject>Adult</subject><subject>Adults</subject><subject>Age</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Global Health</subject><subject>Health Resources</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Illnesses</subject><subject>Immunocompromised Host</subject><subject>Immunologic</subject><subject>Infections</subject><subject>Influenza</subject><subject>Influenza vaccines</subject><subject>Influenza Vaccines - therapeutic use</subject><subject>Influenza, Human</subject><subject>Influenza, Human - epidemiology</subject><subject>Influenza, Human - prevention & control</subject><subject>Medical laboratories</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Older people</subject><subject>Pneumonia</subject><subject>Population</subject><subject>Prevention</subject><subject>Public health</subject><subject>Seasons</subject><subject>Systematic review</subject><subject>Vaccination</subject><subject>Vaccination - economics</subject><subject>Vaccination - legislation & jurisprudence</subject><subject>Vaccination Coverage - statistics & numerical data</subject><subject>Vaccine efficacy</subject><subject>Vaccines</subject><subject>Working groups</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkEtLAzEQgIMotlZ_grLgxcvWyWaTZk9Fii8oeFDBW8gmU0nZR012i_bXm9LqwYswMIf55vURck5hTIGK6-V4rY1xDY4zoHIMMXI4IEMqJyzNOJWHZAiZyNOcwtuAnISwBADOaHFMBgwoZ0XBh2T63Hnd4bvDkHRtUutPV7sNJq5ZVD02G53s1ySuXmnTxULSVhZ9om1fdeGUHC10FfBsn0fk9e72ZfaQzp_uH2c389SwgnWpFCVakU0kp2ilRssNFlbGE6heWIFUSio0GA3MgDQZ8pLygnNRasMZ5mxErnZzV7796DF0qnbBYFXpBts-qAwKwTlIUUT08g-6bHvfxOtUFtUB5GySRYrvKOPbEDwu1Mq7WvsvRUFtDaul2r-utoYVxMgh9l3sp_dljfa360dpBKY7AKOOtUOvgnHYGLTOo-mUbd0_K74BwguOdA</recordid><startdate>20180925</startdate><enddate>20180925</enddate><creator>Whitaker, Jennifer A.</creator><creator>von Itzstein, Mitchell S.</creator><creator>Poland, Gregory A.</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20180925</creationdate><title>Strategies to maximize influenza vaccine impact in older adults</title><author>Whitaker, Jennifer A. ; von Itzstein, Mitchell S. ; Poland, Gregory A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-86bed627851ed8aed5ce9d89951afd6e18816a0ca03c08c2e5b159556bac53e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adjuvants</topic><topic>Adjuvants, Immunologic - administration & dosage</topic><topic>Adult</topic><topic>Adults</topic><topic>Age</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Global Health</topic><topic>Health Resources</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Illnesses</topic><topic>Immunocompromised Host</topic><topic>Immunologic</topic><topic>Infections</topic><topic>Influenza</topic><topic>Influenza vaccines</topic><topic>Influenza Vaccines - therapeutic use</topic><topic>Influenza, Human</topic><topic>Influenza, Human - epidemiology</topic><topic>Influenza, Human - prevention & control</topic><topic>Medical laboratories</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Older people</topic><topic>Pneumonia</topic><topic>Population</topic><topic>Prevention</topic><topic>Public health</topic><topic>Seasons</topic><topic>Systematic review</topic><topic>Vaccination</topic><topic>Vaccination - economics</topic><topic>Vaccination - legislation & jurisprudence</topic><topic>Vaccination Coverage - statistics & numerical data</topic><topic>Vaccine efficacy</topic><topic>Vaccines</topic><topic>Working groups</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whitaker, Jennifer A.</creatorcontrib><creatorcontrib>von Itzstein, Mitchell S.</creatorcontrib><creatorcontrib>Poland, Gregory A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whitaker, Jennifer A.</au><au>von Itzstein, Mitchell S.</au><au>Poland, Gregory A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Strategies to maximize influenza vaccine impact in older adults</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2018-09-25</date><risdate>2018</risdate><volume>36</volume><issue>40</issue><spage>5940</spage><epage>5948</epage><pages>5940-5948</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><abstract>Older adults are disproportionately affected by influenza morbidity and mortality. In most high income countries, influenza vaccine policies target persons age ≥65 years for influenza vaccination. Many low-resource settings do not utilize seasonal influenza vaccination. Barriers to influenza prevention among older adults around the globe are multiple and some vary between high- and low-resource settings. To maximize influenza prevention in the older adult population, gaps in influenza vaccination coverage and improvements in vaccine efficacy are needed. The focus of this article is on the data for currently available vaccine strategies to maximize influenza vaccine impact, with a focus on high-resource settings. We also discuss novel influenza vaccine strategies needed for older adults worldwide.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>30153995</pmid><doi>10.1016/j.vaccine.2018.08.040</doi><tpages>9</tpages></addata></record> |
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| subjects | Adjuvants Adjuvants, Immunologic - administration & dosage Adult Adults Age Age Factors Aged Aged, 80 and over Global Health Health Resources Hospitalization Humans Illnesses Immunocompromised Host Immunologic Infections Influenza Influenza vaccines Influenza Vaccines - therapeutic use Influenza, Human Influenza, Human - epidemiology Influenza, Human - prevention & control Medical laboratories Morbidity Mortality Older people Pneumonia Population Prevention Public health Seasons Systematic review Vaccination Vaccination - economics Vaccination - legislation & jurisprudence Vaccination Coverage - statistics & numerical data Vaccine efficacy Vaccines Working groups |
| title | Strategies to maximize influenza vaccine impact in older adults |
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