The effect of central administration of alpha‐pinene on capsaicin‐induced dental pulp nociception

Aim To assess the effects of central administration of α‐pinene alone and in combination with either bicuculline or naloxone, as GABAA and μ‐opioid receptor antagonists, respectively, on capsaicin‐induced dental pulp stimulation in rats. Methodology Forty‐eight adult male Wistar rats aged 2 months (...

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Veröffentlicht in:	International endodontic journal 2019-03, Vol.52 (3), p.307-317
Hauptverfasser:	Rahbar, I., Abbasnejad, M., Haghani, J., Raoof, M., Kooshki, R., Esmaeili‐Mahani, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha‐pinene Animals Bicuculline Bicuculline - administration & dosage Bicuculline - pharmacology Bicyclic Monoterpenes Capsaicin Capsaicin - administration & dosage Capsaicin - pharmacology Cerebral Ventricles Dental pulp Dental Pulp - drug effects Endodontics Fluorescent Antibody Technique Immunofluorescence Inflammation Male Monoterpenes - administration & dosage Monoterpenes - pharmacology Naloxone Naloxone - administration & dosage Naloxone - pharmacology Narcotics nociception Nociception - drug effects Opioid receptors pain Pain perception Random Allocation Rats Rats, Wistar Rodents Statistical analysis Ventricle (lateral) α-Pinene γ-Aminobutyric acid A receptors
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