Folates in Trypanosoma brucei: Achievements and Opportunities

Trypanosoma brucei is the agent of human African trypanosomiasis (HAT), a neglected disease that threatens the lives of 65 million people in sub‐Saharan Africa every year. Unfortunately, available therapies are unsatisfactory, due primarily to safety issues and development of drug resistance. Over t...

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Veröffentlicht in:	ChemMedChem 2018-10, Vol.13 (20), p.2150-2158
Hauptverfasser:	Cullia, Gregorio, Tamborini, Lucia, Conti, Paola, De Micheli, Carlo, Pinto, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	African trypanosomiasis Chemotherapy Drug resistance Drugs folates Folic acid human African trypanosomiasis Malaria neglected diseases Partnerships Protozoa structure–activity relationships Trypanosoma brucei Vector-borne diseases
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