The Diabetic Phenotype in HNF4A Mutation Carriers Is Moderated By the Expression of HNF4A Isoforms From the P1 Promoter During Fetal Development

The Diabetic Phenotype in HNF4A Mutation Carriers Is Moderated By the Expression of HNF4A Isoforms From the P1 Promoter During Fetal Development Lorna W. Harries 1 , Jonathan M. Locke 1 , Beverley Shields 1 , Neil A. Hanley 2 , Karen Piper Hanley 2 , Anna Steele 1 , Pål R. Njølstad 3 4 , Sian Ellard...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2008-06, Vol.57 (6), p.1745-1752
Hauptverfasser:	Harries, Lorna W, Locke, Jonathan M, Shields, Beverley, Hanley, Neil A, Hanley, Karen Piper, Steele, Anna, Njølstad, Pål R, Ellard, Sian, Hattersley, Andrew T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alternative Splicing Diabetes Diabetes mellitus Diabetes Mellitus - genetics Diabetes Mellitus, Type 2 - genetics European Continental Ancestry Group Female Fetal development Fetal Development - genetics Fetus Gene Expression Profiling Genes Genetic aspects Growth Hepatocyte Nuclear Factor 4 - genetics Humans Hypoglycemia Insulin Kidney - physiology Kidney - physiopathology Male Middle Aged Mutation Pancreas Pancreas - physiology Pancreas - physiopathology Physiological aspects Polymerase Chain Reaction Promoter Regions, Genetic Promoters (Genetics) Protein Isoforms - genetics Proteins Risk factors Transcription factors
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