Molecular docking and 4D-QSAR studies of metastatic cancer inhibitor thiazoles

[Display omitted] •The MCET method was used as the 4D-QSAR method.•3D pharmacophore model have produced by the Klopman index.•Based on the satisfactory LOO-CV method, r2 and q2 results were found.•The study using docking has been compatible with many points of the 3D-PhaM given by MCET. By using the...

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Veröffentlicht in:	Computational biology and chemistry 2018-10, Vol.76, p.327-337
Hauptverfasser:	Türkmenoğlu, Burçin, Güzel, Yahya
Format:	Artikel
Sprache:	eng
Schlagworte:	4D-QSAR MCET Molecular docking Thiazole derivatives
Online-Zugang:	Volltext
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