Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)
The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish ( Danio rerio ). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg -1 of propylparaben, fish in a positive control group were given a...
Gespeichert in:
| Veröffentlicht in: | Acta veterinaria Brno 2009-06, Vol.78 (2), p.319-326 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 326 |
|---|---|
| container_issue | 2 |
| container_start_page | 319 |
| container_title | Acta veterinaria Brno |
| container_volume | 78 |
| creator | Mikula, Přemysl Kružíková, Kamila Dobšíková, Radka Haruštiaková, Danka Svobodová, Zdeňka |
| description | The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben
in vivo
using zebrafish (
Danio rerio
). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg
-1
of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg
-1
of 17β-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg
-1
of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group. |
| doi_str_mv | 10.2754/avb200978020319 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_20935203</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>20935203</sourcerecordid><originalsourceid>FETCH-LOGICAL-c313t-90a3dda35c5f7c9070ee5d74a4afe52d7d4657fb6cac92ac80bc170d2c444b823</originalsourceid><addsrcrecordid>eNpdkEtLxDAUhYMoOIyzdpuV6KLObZI27VLG14ig-Fq4sKTpjQY6SU3awfn3dhhXru6B-3E4fIQcp3DOZCbmal0zgFIWwICn5R6ZpAWkicxkvk8mANvMUn5IZjHaeiRByBz4hHwsnWkHdBqpN_Qx-G7TdiqoGh31jr7ZHtvWf6LDaCNVrqHP-EOfVG89tY7eDWt0tkX6jnVQxsYvenqp3PgMGKw_OyIHRrURZ393Sl6vr14Wt8n9w81ycXGfaJ7yPilB8aZRPNOZkboECYhZI4USymDGGtmIPJOmzrXSJVO6gFqnEhqmhRB1wfiUnOx6u-C_B4x9tbJRj9OVQz_EikHJs1HNCM53oA4-xoCm6oJdqbCpUqi2Kqt_KvkvB59nvQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>20935203</pqid></control><display><type>article</type><title>Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Mikula, Přemysl ; Kružíková, Kamila ; Dobšíková, Radka ; Haruštiaková, Danka ; Svobodová, Zdeňka</creator><creatorcontrib>Mikula, Přemysl ; Kružíková, Kamila ; Dobšíková, Radka ; Haruštiaková, Danka ; Svobodová, Zdeňka</creatorcontrib><description>The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben
in vivo
using zebrafish (
Danio rerio
). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg
-1
of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg
-1
of 17β-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg
-1
of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.</description><identifier>ISSN: 0001-7213</identifier><identifier>EISSN: 1801-7576</identifier><identifier>DOI: 10.2754/avb200978020319</identifier><language>eng</language><subject>Danio rerio ; Freshwater</subject><ispartof>Acta veterinaria Brno, 2009-06, Vol.78 (2), p.319-326</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c313t-90a3dda35c5f7c9070ee5d74a4afe52d7d4657fb6cac92ac80bc170d2c444b823</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Mikula, Přemysl</creatorcontrib><creatorcontrib>Kružíková, Kamila</creatorcontrib><creatorcontrib>Dobšíková, Radka</creatorcontrib><creatorcontrib>Haruštiaková, Danka</creatorcontrib><creatorcontrib>Svobodová, Zdeňka</creatorcontrib><title>Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)</title><title>Acta veterinaria Brno</title><description>The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben
in vivo
using zebrafish (
Danio rerio
). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg
-1
of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg
-1
of 17β-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg
-1
of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.</description><subject>Danio rerio</subject><subject>Freshwater</subject><issn>0001-7213</issn><issn>1801-7576</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNpdkEtLxDAUhYMoOIyzdpuV6KLObZI27VLG14ig-Fq4sKTpjQY6SU3awfn3dhhXru6B-3E4fIQcp3DOZCbmal0zgFIWwICn5R6ZpAWkicxkvk8mANvMUn5IZjHaeiRByBz4hHwsnWkHdBqpN_Qx-G7TdiqoGh31jr7ZHtvWf6LDaCNVrqHP-EOfVG89tY7eDWt0tkX6jnVQxsYvenqp3PgMGKw_OyIHRrURZ393Sl6vr14Wt8n9w81ycXGfaJ7yPilB8aZRPNOZkboECYhZI4USymDGGtmIPJOmzrXSJVO6gFqnEhqmhRB1wfiUnOx6u-C_B4x9tbJRj9OVQz_EikHJs1HNCM53oA4-xoCm6oJdqbCpUqi2Kqt_KvkvB59nvQ</recordid><startdate>20090601</startdate><enddate>20090601</enddate><creator>Mikula, Přemysl</creator><creator>Kružíková, Kamila</creator><creator>Dobšíková, Radka</creator><creator>Haruštiaková, Danka</creator><creator>Svobodová, Zdeňka</creator><scope>AAYXX</scope><scope>CITATION</scope><scope>C1K</scope><scope>F1W</scope><scope>H95</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>20090601</creationdate><title>Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)</title><author>Mikula, Přemysl ; Kružíková, Kamila ; Dobšíková, Radka ; Haruštiaková, Danka ; Svobodová, Zdeňka</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-90a3dda35c5f7c9070ee5d74a4afe52d7d4657fb6cac92ac80bc170d2c444b823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Danio rerio</topic><topic>Freshwater</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mikula, Přemysl</creatorcontrib><creatorcontrib>Kružíková, Kamila</creatorcontrib><creatorcontrib>Dobšíková, Radka</creatorcontrib><creatorcontrib>Haruštiaková, Danka</creatorcontrib><creatorcontrib>Svobodová, Zdeňka</creatorcontrib><collection>CrossRef</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Acta veterinaria Brno</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mikula, Přemysl</au><au>Kružíková, Kamila</au><au>Dobšíková, Radka</au><au>Haruštiaková, Danka</au><au>Svobodová, Zdeňka</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)</atitle><jtitle>Acta veterinaria Brno</jtitle><date>2009-06-01</date><risdate>2009</risdate><volume>78</volume><issue>2</issue><spage>319</spage><epage>326</epage><pages>319-326</pages><issn>0001-7213</issn><eissn>1801-7576</eissn><abstract>The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben
in vivo
using zebrafish (
Danio rerio
). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg
-1
of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg
-1
of 17β-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg
-1
of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.</abstract><doi>10.2754/avb200978020319</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-7213 |
| ispartof | Acta veterinaria Brno, 2009-06, Vol.78 (2), p.319-326 |
| issn | 0001-7213 1801-7576 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_20935203 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Danio rerio Freshwater |
| title | Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T02%3A54%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Influence%20of%20Propylparaben%20on%20Vitellogenesis%20and%20Sex%20Ratio%20in%20Juvenile%20Zebrafish%20(Danio%20rerio)&rft.jtitle=Acta%20veterinaria%20Brno&rft.au=Mikula,%20P%C5%99emysl&rft.date=2009-06-01&rft.volume=78&rft.issue=2&rft.spage=319&rft.epage=326&rft.pages=319-326&rft.issn=0001-7213&rft.eissn=1801-7576&rft_id=info:doi/10.2754/avb200978020319&rft_dat=%3Cproquest_cross%3E20935203%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=20935203&rft_id=info:pmid/&rfr_iscdi=true |