Long-term effects of immunosuppressive therapy on lung function in scleroderma patients

The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration

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Bibliographische Detailangaben
Veröffentlicht in:	Clinical rheumatology 2018-11, Vol.37 (11), p.3043-3050
Hauptverfasser:	Pavlov-Dolijanovic, Slavica, Vujasinovic Stupar, Nada, Zugic, Vladimir, Ostojic, Predrag, Zekovic, Ana, Zivanovic Radnic, Tatjana, Jeremic, Ivan, Tadic, Ivana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Azathioprine Carbon monoxide Carbon Monoxide - blood Cyclophosphamide Cyclophosphamide - administration & dosage Female Humans Immunosuppressive agents Immunosuppressive Agents - administration & dosage Long-term effects Lung - physiopathology Male Medicine Medicine & Public Health Methotrexate Middle Aged Mycophenolate mofetil Mycophenolic acid Original Article Patients Pulse Therapy, Drug - methods Respiratory function Rheumatology Scleroderma Scleroderma, Systemic - drug therapy Scleroderma, Systemic - physiopathology Systemic sclerosis Time Factors Treatment Outcome Vital Capacity
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Beschreibung
Zusammenfassung:	The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration
ISSN:	0770-3198 1434-9949
DOI:	10.1007/s10067-018-4266-0