Finding Better Ways to Prevent Postpartum Hemorrhage
Postpartum hemorrhage is the leading cause of maternal death in low-income countries. 1 Although moderate bleeding after childbirth is not problematic in most healthy mothers, it can be life-threatening in mothers with clinically significant anemia, and severe bleeding can be rapidly fatal. Preventi...
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| Veröffentlicht in: | The New England journal of medicine 2018-08, Vol.379 (8), p.790-792 |
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| container_title | The New England journal of medicine |
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| creator | Shakur-Still, Haleema Roberts, Ian |
| description | Postpartum hemorrhage is the leading cause of maternal death in low-income countries.
1
Although moderate bleeding after childbirth is not problematic in most healthy mothers, it can be life-threatening in mothers with clinically significant anemia, and severe bleeding can be rapidly fatal. Prevention of excessive postpartum bleeding is essential. The administration of drugs to contract the uterus (uterotonic agents) immediately after delivery is the cornerstone of strategies to prevent excessive postpartum bleeding.
2
The uterine smooth muscle is believed to act as a living ligature that compresses bleeding blood vessels, stemming the flow of blood. Although there are remarkably few high-quality trials . . . |
| doi_str_mv | 10.1056/NEJMe1808500 |
| format | Article |
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1
Although moderate bleeding after childbirth is not problematic in most healthy mothers, it can be life-threatening in mothers with clinically significant anemia, and severe bleeding can be rapidly fatal. Prevention of excessive postpartum bleeding is essential. The administration of drugs to contract the uterus (uterotonic agents) immediately after delivery is the cornerstone of strategies to prevent excessive postpartum bleeding.
2
The uterine smooth muscle is believed to act as a living ligature that compresses bleeding blood vessels, stemming the flow of blood. Although there are remarkably few high-quality trials . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMe1808500</identifier><identifier>PMID: 30134138</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Acids ; Anemia ; Bleeding ; Blood vessels ; Childbirth & labor ; Hemorrhage ; Postpartum ; Prevention ; Regulatory approval ; Smooth muscle ; Uterus ; Women</subject><ispartof>The New England journal of medicine, 2018-08, Vol.379 (8), p.790-792</ispartof><rights>Copyright © 2018 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-1b67c1888fac8cfee84f10239fa35bbb1e39d3fb20bbaebaa9fa65473c671ef3</citedby><cites>FETCH-LOGICAL-c386t-1b67c1888fac8cfee84f10239fa35bbb1e39d3fb20bbaebaa9fa65473c671ef3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMe1808500$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2091888612?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30134138$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shakur-Still, Haleema</creatorcontrib><creatorcontrib>Roberts, Ian</creatorcontrib><title>Finding Better Ways to Prevent Postpartum Hemorrhage</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Postpartum hemorrhage is the leading cause of maternal death in low-income countries.
1
Although moderate bleeding after childbirth is not problematic in most healthy mothers, it can be life-threatening in mothers with clinically significant anemia, and severe bleeding can be rapidly fatal. Prevention of excessive postpartum bleeding is essential. The administration of drugs to contract the uterus (uterotonic agents) immediately after delivery is the cornerstone of strategies to prevent excessive postpartum bleeding.
2
The uterine smooth muscle is believed to act as a living ligature that compresses bleeding blood vessels, stemming the flow of blood. Although there are remarkably few high-quality trials . . .</description><subject>Acids</subject><subject>Anemia</subject><subject>Bleeding</subject><subject>Blood vessels</subject><subject>Childbirth & labor</subject><subject>Hemorrhage</subject><subject>Postpartum</subject><subject>Prevention</subject><subject>Regulatory approval</subject><subject>Smooth muscle</subject><subject>Uterus</subject><subject>Women</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpt0MFLwzAUBvAgipvTm2cp6MGD1aRJ2_SoY3PK1B0GHkvSvcyOpdmSVNh_b8amiPguObwfXx4fQucE3xKcZnevg-cXIBzzFOMD1CUppTFjODtEXYwTHrO8oB104twChyGsOEYdigllhPIuYsO6mdXNPHoA78FG72LjIm-iiYVPaHw0Mc6vhPWtjkagjbUfYg6n6EiJpYOz_dtD0-Fg2h_F47fHp_79OK4oz3xMZJZXhHOuRMUrBcCZIjihhRI0lVISoMWMKplgKQVIIcIiS1lOqywnoGgPXe9iV9asW3C-1LWrYLkUDZjWlQkukpTm4YNAL__QhWltE47bqu0NGUmCutmpyhrnLKhyZWst7KYkuNyWWf4uM_CLfWgrNcx-8Hd7AVztgNaubGCh_8_5AlbzeRw</recordid><startdate>20180823</startdate><enddate>20180823</enddate><creator>Shakur-Still, Haleema</creator><creator>Roberts, Ian</creator><general>Massachusetts Medical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20180823</creationdate><title>Finding Better Ways to Prevent Postpartum Hemorrhage</title><author>Shakur-Still, Haleema ; Roberts, Ian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-1b67c1888fac8cfee84f10239fa35bbb1e39d3fb20bbaebaa9fa65473c671ef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Acids</topic><topic>Anemia</topic><topic>Bleeding</topic><topic>Blood vessels</topic><topic>Childbirth & labor</topic><topic>Hemorrhage</topic><topic>Postpartum</topic><topic>Prevention</topic><topic>Regulatory approval</topic><topic>Smooth muscle</topic><topic>Uterus</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shakur-Still, Haleema</creatorcontrib><creatorcontrib>Roberts, Ian</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shakur-Still, Haleema</au><au>Roberts, Ian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Finding Better Ways to Prevent Postpartum Hemorrhage</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2018-08-23</date><risdate>2018</risdate><volume>379</volume><issue>8</issue><spage>790</spage><epage>792</epage><pages>790-792</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>Postpartum hemorrhage is the leading cause of maternal death in low-income countries.
1
Although moderate bleeding after childbirth is not problematic in most healthy mothers, it can be life-threatening in mothers with clinically significant anemia, and severe bleeding can be rapidly fatal. Prevention of excessive postpartum bleeding is essential. The administration of drugs to contract the uterus (uterotonic agents) immediately after delivery is the cornerstone of strategies to prevent excessive postpartum bleeding.
2
The uterine smooth muscle is believed to act as a living ligature that compresses bleeding blood vessels, stemming the flow of blood. Although there are remarkably few high-quality trials . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>30134138</pmid><doi>10.1056/NEJMe1808500</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The New England journal of medicine, 2018-08, Vol.379 (8), p.790-792 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Acids Anemia Bleeding Blood vessels Childbirth & labor Hemorrhage Postpartum Prevention Regulatory approval Smooth muscle Uterus Women |
| title | Finding Better Ways to Prevent Postpartum Hemorrhage |
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