Model visualization for evaluation of biocatalytic processes

Biocatalysis offers great potential as an additional, and in some cases as an alternative, synthetic tool for organic chemists, especially as a route to introduce chirality. However, the implementation of scalable biocatalytic processes nearly always requires the introduction of process and/or bioca...

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Veröffentlicht in:Food and bioproducts processing 2008-06, Vol.86 (2), p.96-103
Hauptverfasser: Law, H.E.M., Lewis, D.J., McRobbie, I., Woodley, J.M.
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container_end_page 103
container_issue 2
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container_title Food and bioproducts processing
container_volume 86
creator Law, H.E.M.
Lewis, D.J.
McRobbie, I.
Woodley, J.M.
description Biocatalysis offers great potential as an additional, and in some cases as an alternative, synthetic tool for organic chemists, especially as a route to introduce chirality. However, the implementation of scalable biocatalytic processes nearly always requires the introduction of process and/or biocatalyst enhancements to ensure effective scale-up. This paper describes a paradigm for the purpose of evaluating biocatalytic processes in order to provide guidance on process and biocatalyst modification. The paradigm is illustrated with the biocatalytic synthesis of S, S-ethylenediaminedisuccinic acid ( S, S-EDDS), a biodegradable chelant, and is characterised by the use of model visualization using ‘windows of operation’.
doi_str_mv 10.1016/j.fbp.2008.03.006
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subjects Bidegradable chelant
Biocatalysis
Biological and medical sciences
Food industries
Fundamental and applied biological sciences. Psychology
Modeling
title Model visualization for evaluation of biocatalytic processes
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