Extrahepatic Upregulation of Transforming Growth Factor Beta 2 in HCV Genotype 4-Induced Liver Fibrosis

Elevated levels of transforming growth factor-β (TGF-β) family mediate myofibroblast generation and extracellular matrix deposition, thus making TGF-β recognized as major profibrogenic cytokines. In this article, we provide evidence that extrahepatic TGF-β2 expression at RNA and protein levels in pe...

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Veröffentlicht in:	Journal of interferon & cytokine research 2018-08, Vol.38 (8), p.341-347
Hauptverfasser:	Abd El-Meguid, Mai, Dawood, Reham M, Mokhles, Mohamed Aly, El Awady, Mostafa K
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biotechnology Cell cycle Cell growth Correlation analysis Cytokines Enzyme-linked immunosorbent assay Extracellular matrix Fibrosis Gene expression Genetic engineering Genotypes Growth factors Hepatitis Hepatitis C Infections Kinases Leukocytes Liver Liver cancer Liver diseases Patients Phosphorylation Protein A Proteins Research centers Ribonucleic acid RNA Transcription Transforming growth factor-b1 Tumors Up-regulation Viruses
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