TLR2 Promotes Glioma Immune Evasion by Downregulating MHC Class II Molecules in Microglia

Gliomas, the most common primary neoplasms in the brain, are notorious for their ability to evade the immune response. Despite microglial infiltration in gliomas, expression of MHC class II molecules in those microglia is compromised. Here, we report that Toll-like receptor 2 (TLR2) activation downr...

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Veröffentlicht in:	Cancer immunology research 2018-10, Vol.6 (10), p.1220-1233
Hauptverfasser:	Qian, Jiawen, Luo, Feifei, Yang, Jiao, Liu, Jun, Liu, Ronghua, Wang, Luman, Wang, Chen, Deng, Yuting, Lu, Zhou, Wang, Yuedi, Lu, Mingfang, Wang, Ji-Yang, Chu, Yiwei
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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