FOXO3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy

Embryo implantation is essential for normal pregnancy, and the process of decidualization is critical for embryo implantation. However, the mechanism of decidualization during early pregnancy is still unknown. Forkhead box O3a (FOXO3a) is the most important functional transcription factor of the for...

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Veröffentlicht in:	Journal of cellular physiology 2019-04, Vol.234 (4), p.4154-4166
Hauptverfasser:	Long, Jing, Yang, Cheng‐Shun, He, Jun‐Lin, Liu, Xue‐Qing, Ding, Yu‐Bin, Chen, Xue‐Mei, Tong, Chao, Peng, Chuan, Wang, Ying‐Xiong, Gao, Ru‐Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Spontaneous - metabolism Abortion, Spontaneous - pathology Animals Apoptosis Decidua decidualization Embryo Implantation Embryos Endometrium Endometrium - metabolism Female Forkhead Box Protein O3 - genetics Forkhead Box Protein O3 - metabolism Forkhead protein FOXO3 protein FOXO3a Gene expression Humans Implantation Mice Pregnancy Ribonucleic acid RNA Signal Transduction siRNA Stromal cells Stromal Cells - metabolism Surgical implants Time Factors Transcription factors Up-Regulation Uterus
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