Loss of long non-coding RNA CRRL promotes cardiomyocyte regeneration and improves cardiac repair by functioning as a competing endogenous RNA

Long noncoding RNAs (lncRNAs) play critical roles in the development of myocardial hypertrophy and may stimulate endogenous myocardial regeneration to prevent heart failure after myocardial infarction (MI). However, whether lncRNAs are involved in regulating myocardial regeneration after MI remains...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2018-09, Vol.122, p.152-164
Hauptverfasser:	Chen, Guojun, Li, Hairui, Li, Xinzhong, Li, Bing, Zhong, Lintao, Huang, Senlin, Zheng, Hao, Li, Mengsha, Jin, Guoqing, Liao, Wangjun, Liao, Yulin, Chen, Yanmei, Bin, Jianping
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Cardiomegaly - metabolism Cardiomyocyte proliferation Cell Proliferation Competing endogenous RNAs Computational Biology Databases, Nucleic Acid Disease Models, Animal Gene Knockdown Techniques Homeodomain Proteins - metabolism Humans Long noncoding RNAs MicroRNAs - metabolism Myocardial Infarction - metabolism Myocardial regeneration Myocytes, Cardiac - metabolism Rats Rats, Sprague-Dawley Recovery of Function Regeneration - physiology RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Statistics, Nonparametric Transfection Ventricular Remodeling
Online-Zugang:	Volltext
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