Testosterone and Follicle Stimulating Hormone–Dependent Glyoxalase 1 Up-Regulation Sustains the Viability of Porcine Sertoli Cells through the Control of Hydroimidazolone– and Argpyrimidine-Mediated NF-κB Pathway

Because Sertoli cells (SCs) play a central role in germ cell survival, their death may result in marked germ cell loss and infertility. SCs are the only somatic cells within the seminiferous tubules and are essential for regulating spermatogenesis. Factors that enhance or diminish the viability of S...

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Veröffentlicht in:	The American journal of pathology 2018-11, Vol.188 (11), p.2553-2563
Hauptverfasser:	Antognelli, Cinzia, Mancuso, Francesca, Frosini, Roberta, Arato, Iva, Calvitti, Mario, Calafiore, Riccardo, Talesa, Vincenzo N., Luca, Giovanni
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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