Predictive Value of Mild Cognitive Impairment for Dementia
Background/Aims: In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. Methods...
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| Veröffentlicht in: | Dementia and geriatric cognitive disorders 2009-03, Vol.27 (2), p.173-181 |
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| container_title | Dementia and geriatric cognitive disorders |
| container_volume | 27 |
| creator | Baars, M.A.E. van Boxtel, M.P.J. Dijkstra, J.B. Visser, P.J. van den Akker, M. Verhey, F.R.J. Jolles, J. |
| description | Background/Aims: In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. Methods: This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study. Results: MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity: 0.66, specificity: 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60–70 years: sensitivity = 0.56; age 70–85 years: sensitivity = 0.70). Conclusion: The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints. |
| doi_str_mv | 10.1159/000200465 |
| format | Article |
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This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. Methods: This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study. Results: MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity: 0.66, specificity: 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60–70 years: sensitivity = 0.56; age 70–85 years: sensitivity = 0.70). Conclusion: The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints.</description><identifier>ISSN: 1420-8008</identifier><identifier>EISSN: 1421-9824</identifier><identifier>DOI: 10.1159/000200465</identifier><identifier>PMID: 19202336</identifier><identifier>CODEN: DGCDFX</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Dementia ; Original Research Article</subject><ispartof>Dementia and geriatric cognitive disorders, 2009-03, Vol.27 (2), p.173-181</ispartof><rights>2009 S. Karger AG, Basel</rights><rights>Copyright (c) 2009 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2194-2e3c646af7a04ece82fbb8710ca102c8e6833f364682cf2b2d2afcca60a5ab633</citedby><cites>FETCH-LOGICAL-c2194-2e3c646af7a04ece82fbb8710ca102c8e6833f364682cf2b2d2afcca60a5ab633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2429,27924,27925</link.rule.ids></links><search><creatorcontrib>Baars, M.A.E.</creatorcontrib><creatorcontrib>van Boxtel, M.P.J.</creatorcontrib><creatorcontrib>Dijkstra, J.B.</creatorcontrib><creatorcontrib>Visser, P.J.</creatorcontrib><creatorcontrib>van den Akker, M.</creatorcontrib><creatorcontrib>Verhey, F.R.J.</creatorcontrib><creatorcontrib>Jolles, J.</creatorcontrib><title>Predictive Value of Mild Cognitive Impairment for Dementia</title><title>Dementia and geriatric cognitive disorders</title><addtitle>Dement Geriatr Cogn Disord</addtitle><description>Background/Aims: In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. Methods: This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study. Results: MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity: 0.66, specificity: 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60–70 years: sensitivity = 0.56; age 70–85 years: sensitivity = 0.70). Conclusion: The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints.</description><subject>Dementia</subject><subject>Original Research Article</subject><issn>1420-8008</issn><issn>1421-9824</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpd0DtPwzAQB3ALgWgpDOwMEQMSQ-B8ThyHDZVXpSIYgDVy3HPlkkexGyS-PelDDEz3191Pp9MxdsrhivM0vwYABEhkuseGPEEe5wqT_U2GWAGoATsKYdGzLJX5IRvwHAGFkEN28-pp5szKfVP0oauOotZGz66aReN23rhNf1IvtfM1NavItj66o3V0-pgdWF0FOtnVEXt_uH8bP8XTl8fJ-HYaG-R5EiMJIxOpbaYhIUMKbVmqjIPRHNAokkoIK3qi0FgscYbaGqMl6FSXUogRu9juXfr2q6OwKmoXDFWVbqjtQoGQcy4h6eH5P7hoO9_0txUoMAWVwXrb5RYZ34bgyRZL72rtfwoOxfqbxd83e3u2tZ_az8n_yd34F9pabDw</recordid><startdate>20090301</startdate><enddate>20090301</enddate><creator>Baars, M.A.E.</creator><creator>van Boxtel, M.P.J.</creator><creator>Dijkstra, J.B.</creator><creator>Visser, P.J.</creator><creator>van den Akker, M.</creator><creator>Verhey, F.R.J.</creator><creator>Jolles, J.</creator><general>S. 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This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. Methods: This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study. Results: MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity: 0.66, specificity: 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60–70 years: sensitivity = 0.56; age 70–85 years: sensitivity = 0.70). Conclusion: The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>19202336</pmid><doi>10.1159/000200465</doi><tpages>9</tpages></addata></record> |
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| source | Karger Journals Complete; Alma/SFX Local Collection |
| subjects | Dementia Original Research Article |
| title | Predictive Value of Mild Cognitive Impairment for Dementia |
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