Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting
Background: It is well known that nutritional habits, sleeping patterns and meal frequency have profound effects on maintaining human health. Ramadan is a religious month for Islam, during which Muslims do not eat and drink during the daylight hours. The duration of restricted food and beverage inta...
Gespeichert in:
| Veröffentlicht in: | Annals of nutrition and metabolism 2007-01, Vol.51 (1), p.88-95 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 95 |
|---|---|
| container_issue | 1 |
| container_start_page | 88 |
| container_title | Annals of nutrition and metabolism |
| container_volume | 51 |
| creator | Aksungar, Fehime B. Topkaya, Aynur E. Akyildiz, Mahmut |
| description | Background: It is well known that nutritional habits, sleeping patterns and meal frequency have profound effects on maintaining human health. Ramadan is a religious month for Islam, during which Muslims do not eat and drink during the daylight hours. The duration of restricted food and beverage intake is approximately 12 h/day for 1 month, which makes Ramadan a model of prolonged intermittent fasting. Methods: In order to evaluate the effects of long-lasting modifications of food intake on inflammatory markers and biochemical parameters 40 healthy volunteers of normal weight 20 females aged between 20 and 38 years, 20 males aged between 23 and 39 years, body mass index (BMI) |
| doi_str_mv | 10.1159/000100954 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_20910798</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>48507646</jstor_id><sourcerecordid>48507646</sourcerecordid><originalsourceid>FETCH-LOGICAL-c408t-af4017e23e367bfcf302bde5e62368a87ddc6cee04463a22b13a4f2d21dbcff93</originalsourceid><addsrcrecordid>eNqF0ctv1DAQBnALgei2cODOI-KAhERg_IgfR7QqUKkSB-g5cpzx4m3ibG0Hif-erLKiiAsnH77ffBprCHlG4T2ljfkAABTANOIB2VDBaG2kUQ_JBlgDtdSgzsh5zvtFMS2ax-SMKq6EEXpDuqtYMA0434ZYy3fVtk5oXQk_sTqkqWCIlY191YXJ_cAxODtUB5vsiMtUrvo5hbg7ymGKO-yrcGwbQykYS-VtLkv8hDzydsj49PRekJtPl9-3X-rrr5-vth-vaydAl9p6AVQh48il6rzzHFjXY4OScamtVn3vpEMEISS3jHWUW-FZz2jfOe8NvyBv1t5lnbsZc2nHkB0Og404zblVIMAYqf4LGRgKyugFvv4H7qc5xeUTLeOMglFaLujtilyack7o20MKo02_Wgrt8Tztn_Ms9uWpcO5G7O_l6R4LeL6CW5t2mP6qOs2_WON9LtN9KnQDSorjLq_W3NuptbsUcnvzjQHlAEozyiT_DYLTpqA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>232109786</pqid></control><display><type>article</type><title>Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>Karger Journals</source><source>Alma/SFX Local Collection</source><creator>Aksungar, Fehime B. ; Topkaya, Aynur E. ; Akyildiz, Mahmut</creator><creatorcontrib>Aksungar, Fehime B. ; Topkaya, Aynur E. ; Akyildiz, Mahmut</creatorcontrib><description>Background: It is well known that nutritional habits, sleeping patterns and meal frequency have profound effects on maintaining human health. Ramadan is a religious month for Islam, during which Muslims do not eat and drink during the daylight hours. The duration of restricted food and beverage intake is approximately 12 h/day for 1 month, which makes Ramadan a model of prolonged intermittent fasting. Methods: In order to evaluate the effects of long-lasting modifications of food intake on inflammatory markers and biochemical parameters 40 healthy volunteers of normal weight 20 females aged between 20 and 38 years, 20 males aged between 23 and 39 years, body mass index (BMI) <25 kg/m2 who fasted during Ramadan and another 28 healthy age- and BMI-matched volunteers (14 males, 14 females) who did not fast participated in the study. Venous blood samples were taken 1 week before Ramadan, during the last week of Ramadan and 3 weeks after Ramadan. Serum interleukin-6 (IL-6), C-reactive protein (CRP), homocysteine, vitamin B12, folate, total cholesterol (TC), triglycerides, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels were measured. Results: No significant changes were observed in serum total cholesterol, triglycerides and LDL levels. TC/HDL ratio (HDL risk factor) was decreased during and after Ramadan in both genders in the fasting group while there were no changes in the nonfasting group. IL-6 (p < 0.001), CRP (p < 0.001) and homocysteine (p < 0.01) levels were significantly low during Ramadan in the fasting subjects of both genders when compared to basal values (1 week before Ramadan). Conclusion: Our results demonstrate that prolonged intermittent fasting in a model like Ramadan has some positive effects on the inflammatory status of the body and on the risk factors for cardiovascular diseases such as homocysteine, CRP and TC/HDL ratio.</description><identifier>ISSN: 0250-6807</identifier><identifier>EISSN: 1421-9697</identifier><identifier>DOI: 10.1159/000100954</identifier><identifier>PMID: 17374948</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Adult ; Biochemistry ; Biomarkers - blood ; blood lipids ; blood serum ; C-reactive protein ; C-Reactive Protein - analysis ; Cardiovascular diseases ; Cholesterol ; Diet ; Fasting ; Fasting - blood ; Female ; folic acid ; high density lipoprotein ; homocysteine ; Homocysteine - blood ; human nutrition ; Humans ; inflammation ; interleukin-6 ; Interleukin-6 - blood ; Islam ; Lipids - blood ; long term effects ; Male ; Nutrition ; Original Paper ; oxidative stress ; Ramadan ; Risk factors ; Vitamin B Complex - blood ; vitamin B12</subject><ispartof>Annals of nutrition and metabolism, 2007-01, Vol.51 (1), p.88-95</ispartof><rights>2007 S. Karger AG</rights><rights>2007 S. Karger AG, Basel</rights><rights>Copyright 2007 S. Karger AG, Basel.</rights><rights>Copyright (c) 2007 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-af4017e23e367bfcf302bde5e62368a87ddc6cee04463a22b13a4f2d21dbcff93</citedby><cites>FETCH-LOGICAL-c408t-af4017e23e367bfcf302bde5e62368a87ddc6cee04463a22b13a4f2d21dbcff93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/48507646$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/48507646$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2427,27922,27923,58015,58248</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17374948$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aksungar, Fehime B.</creatorcontrib><creatorcontrib>Topkaya, Aynur E.</creatorcontrib><creatorcontrib>Akyildiz, Mahmut</creatorcontrib><title>Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting</title><title>Annals of nutrition and metabolism</title><addtitle>Ann Nutr Metab</addtitle><description>Background: It is well known that nutritional habits, sleeping patterns and meal frequency have profound effects on maintaining human health. Ramadan is a religious month for Islam, during which Muslims do not eat and drink during the daylight hours. The duration of restricted food and beverage intake is approximately 12 h/day for 1 month, which makes Ramadan a model of prolonged intermittent fasting. Methods: In order to evaluate the effects of long-lasting modifications of food intake on inflammatory markers and biochemical parameters 40 healthy volunteers of normal weight 20 females aged between 20 and 38 years, 20 males aged between 23 and 39 years, body mass index (BMI) <25 kg/m2 who fasted during Ramadan and another 28 healthy age- and BMI-matched volunteers (14 males, 14 females) who did not fast participated in the study. Venous blood samples were taken 1 week before Ramadan, during the last week of Ramadan and 3 weeks after Ramadan. Serum interleukin-6 (IL-6), C-reactive protein (CRP), homocysteine, vitamin B12, folate, total cholesterol (TC), triglycerides, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels were measured. Results: No significant changes were observed in serum total cholesterol, triglycerides and LDL levels. TC/HDL ratio (HDL risk factor) was decreased during and after Ramadan in both genders in the fasting group while there were no changes in the nonfasting group. IL-6 (p < 0.001), CRP (p < 0.001) and homocysteine (p < 0.01) levels were significantly low during Ramadan in the fasting subjects of both genders when compared to basal values (1 week before Ramadan). Conclusion: Our results demonstrate that prolonged intermittent fasting in a model like Ramadan has some positive effects on the inflammatory status of the body and on the risk factors for cardiovascular diseases such as homocysteine, CRP and TC/HDL ratio.</description><subject>Adult</subject><subject>Biochemistry</subject><subject>Biomarkers - blood</subject><subject>blood lipids</subject><subject>blood serum</subject><subject>C-reactive protein</subject><subject>C-Reactive Protein - analysis</subject><subject>Cardiovascular diseases</subject><subject>Cholesterol</subject><subject>Diet</subject><subject>Fasting</subject><subject>Fasting - blood</subject><subject>Female</subject><subject>folic acid</subject><subject>high density lipoprotein</subject><subject>homocysteine</subject><subject>Homocysteine - blood</subject><subject>human nutrition</subject><subject>Humans</subject><subject>inflammation</subject><subject>interleukin-6</subject><subject>Interleukin-6 - blood</subject><subject>Islam</subject><subject>Lipids - blood</subject><subject>long term effects</subject><subject>Male</subject><subject>Nutrition</subject><subject>Original Paper</subject><subject>oxidative stress</subject><subject>Ramadan</subject><subject>Risk factors</subject><subject>Vitamin B Complex - blood</subject><subject>vitamin B12</subject><issn>0250-6807</issn><issn>1421-9697</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0ctv1DAQBnALgei2cODOI-KAhERg_IgfR7QqUKkSB-g5cpzx4m3ibG0Hif-erLKiiAsnH77ffBprCHlG4T2ljfkAABTANOIB2VDBaG2kUQ_JBlgDtdSgzsh5zvtFMS2ax-SMKq6EEXpDuqtYMA0434ZYy3fVtk5oXQk_sTqkqWCIlY191YXJ_cAxODtUB5vsiMtUrvo5hbg7ymGKO-yrcGwbQykYS-VtLkv8hDzydsj49PRekJtPl9-3X-rrr5-vth-vaydAl9p6AVQh48il6rzzHFjXY4OScamtVn3vpEMEISS3jHWUW-FZz2jfOe8NvyBv1t5lnbsZc2nHkB0Og404zblVIMAYqf4LGRgKyugFvv4H7qc5xeUTLeOMglFaLujtilyack7o20MKo02_Wgrt8Tztn_Ms9uWpcO5G7O_l6R4LeL6CW5t2mP6qOs2_WON9LtN9KnQDSorjLq_W3NuptbsUcnvzjQHlAEozyiT_DYLTpqA</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Aksungar, Fehime B.</creator><creator>Topkaya, Aynur E.</creator><creator>Akyildiz, Mahmut</creator><general>S. Karger AG</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20070101</creationdate><title>Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting</title><author>Aksungar, Fehime B. ; Topkaya, Aynur E. ; Akyildiz, Mahmut</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-af4017e23e367bfcf302bde5e62368a87ddc6cee04463a22b13a4f2d21dbcff93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Biochemistry</topic><topic>Biomarkers - blood</topic><topic>blood lipids</topic><topic>blood serum</topic><topic>C-reactive protein</topic><topic>C-Reactive Protein - analysis</topic><topic>Cardiovascular diseases</topic><topic>Cholesterol</topic><topic>Diet</topic><topic>Fasting</topic><topic>Fasting - blood</topic><topic>Female</topic><topic>folic acid</topic><topic>high density lipoprotein</topic><topic>homocysteine</topic><topic>Homocysteine - blood</topic><topic>human nutrition</topic><topic>Humans</topic><topic>inflammation</topic><topic>interleukin-6</topic><topic>Interleukin-6 - blood</topic><topic>Islam</topic><topic>Lipids - blood</topic><topic>long term effects</topic><topic>Male</topic><topic>Nutrition</topic><topic>Original Paper</topic><topic>oxidative stress</topic><topic>Ramadan</topic><topic>Risk factors</topic><topic>Vitamin B Complex - blood</topic><topic>vitamin B12</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aksungar, Fehime B.</creatorcontrib><creatorcontrib>Topkaya, Aynur E.</creatorcontrib><creatorcontrib>Akyildiz, Mahmut</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of nutrition and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aksungar, Fehime B.</au><au>Topkaya, Aynur E.</au><au>Akyildiz, Mahmut</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting</atitle><jtitle>Annals of nutrition and metabolism</jtitle><addtitle>Ann Nutr Metab</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>51</volume><issue>1</issue><spage>88</spage><epage>95</epage><pages>88-95</pages><issn>0250-6807</issn><eissn>1421-9697</eissn><abstract>Background: It is well known that nutritional habits, sleeping patterns and meal frequency have profound effects on maintaining human health. Ramadan is a religious month for Islam, during which Muslims do not eat and drink during the daylight hours. The duration of restricted food and beverage intake is approximately 12 h/day for 1 month, which makes Ramadan a model of prolonged intermittent fasting. Methods: In order to evaluate the effects of long-lasting modifications of food intake on inflammatory markers and biochemical parameters 40 healthy volunteers of normal weight 20 females aged between 20 and 38 years, 20 males aged between 23 and 39 years, body mass index (BMI) <25 kg/m2 who fasted during Ramadan and another 28 healthy age- and BMI-matched volunteers (14 males, 14 females) who did not fast participated in the study. Venous blood samples were taken 1 week before Ramadan, during the last week of Ramadan and 3 weeks after Ramadan. Serum interleukin-6 (IL-6), C-reactive protein (CRP), homocysteine, vitamin B12, folate, total cholesterol (TC), triglycerides, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels were measured. Results: No significant changes were observed in serum total cholesterol, triglycerides and LDL levels. TC/HDL ratio (HDL risk factor) was decreased during and after Ramadan in both genders in the fasting group while there were no changes in the nonfasting group. IL-6 (p < 0.001), CRP (p < 0.001) and homocysteine (p < 0.01) levels were significantly low during Ramadan in the fasting subjects of both genders when compared to basal values (1 week before Ramadan). Conclusion: Our results demonstrate that prolonged intermittent fasting in a model like Ramadan has some positive effects on the inflammatory status of the body and on the risk factors for cardiovascular diseases such as homocysteine, CRP and TC/HDL ratio.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>17374948</pmid><doi>10.1159/000100954</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0250-6807 |
| ispartof | Annals of nutrition and metabolism, 2007-01, Vol.51 (1), p.88-95 |
| issn | 0250-6807 1421-9697 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_20910798 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; Karger Journals; Alma/SFX Local Collection |
| subjects | Adult Biochemistry Biomarkers - blood blood lipids blood serum C-reactive protein C-Reactive Protein - analysis Cardiovascular diseases Cholesterol Diet Fasting Fasting - blood Female folic acid high density lipoprotein homocysteine Homocysteine - blood human nutrition Humans inflammation interleukin-6 Interleukin-6 - blood Islam Lipids - blood long term effects Male Nutrition Original Paper oxidative stress Ramadan Risk factors Vitamin B Complex - blood vitamin B12 |
| title | Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T19%3A26%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Interleukin-6,%20C-reactive%20protein%20and%20biochemical%20parameters%20during%20prolonged%20intermittent%20fasting&rft.jtitle=Annals%20of%20nutrition%20and%20metabolism&rft.au=Aksungar,%20Fehime%20B.&rft.date=2007-01-01&rft.volume=51&rft.issue=1&rft.spage=88&rft.epage=95&rft.pages=88-95&rft.issn=0250-6807&rft.eissn=1421-9697&rft_id=info:doi/10.1159/000100954&rft_dat=%3Cjstor_proqu%3E48507646%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=232109786&rft_id=info:pmid/17374948&rft_jstor_id=48507646&rfr_iscdi=true |