Acute exacerbation of hepatitis due to reactivation of hepatitis B virus with mutations in the core region after chemotherapy for malignant lymphoma

A 43-year-old Japanese man who was positive for hepatitis B surface (HBs) antigen and HB e antibody, underwent chemotherapy for non-Hodgkin's lymphoma. After the chemotherapy he suffered from acute exacerbation of hepatitis because of reactivation of HBV. Recovery was achieved with interferon-a...

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Veröffentlicht in:	Journal of gastroenterology 1997-10, Vol.32 (5), p.668-671
Hauptverfasser:	Sato, T, Kato, J, Kawanishi, J, Kogawa, K, Ohya, M, Sakamaki, S, Niitsu, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Antigenicity Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biopsy Chemotherapy Codons Cyclophosphamide - adverse effects Cyclophosphamide - therapeutic use Cytotoxicity DNA Primers - chemistry DNA, Viral - analysis Doxorubicin - adverse effects Doxorubicin - therapeutic use Follow-Up Studies Glucagon Glucosinolates - immunology Hepatitis B Hepatitis B - etiology Hepatitis B - pathology Hepatitis B Antibodies - analysis Hepatitis B Core Antigens - drug effects Hepatitis B Core Antigens - genetics Hepatitis B virus Hepatitis B virus - drug effects Hepatitis B virus - genetics Hepatitis B virus - growth & development Humans Insulin Lymphocytes T Lymphoma, Non-Hodgkin - drug therapy Male Mutation Mutation - genetics Non-Hodgkin's lymphoma Polymerase Chain Reaction Prednisone - adverse effects Prednisone - therapeutic use Vincristine - adverse effects Vincristine - therapeutic use Virus Activation - drug effects α-Interferon
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