Successful Treatment of Steroid-Resistant Minimal Change Disease with Mycophenolate Mofetil
Mycophenolate mofetil has been reported to be effective in the treatment of steroid-responsive minimal change disease. We report a case of steroid- and cyclosporin-resistant minimal change disease with severe nephrotic syndrome that responded to mycophenolate mofetil with complete remission. The pat...
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Veröffentlicht in: | American journal of nephrology 2002-09, Vol.22 (5-6), p.569-572 |
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container_title | American journal of nephrology |
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creator | Mogyorósi, András Lippman, H. Robert Feldman, George M. |
description | Mycophenolate mofetil has been reported to be effective in the treatment of steroid-responsive minimal change disease. We report a case of steroid- and cyclosporin-resistant minimal change disease with severe nephrotic syndrome that responded to mycophenolate mofetil with complete remission. The patient remains in complete remission 1 year after the discontinuation of mycophenolate mofetil. The presented case argues for the need of a prospective controlled study with the goal of evaluating the efficacy of mycophenolate mofetil in the therapy of steroid-resistant minimal change disease. |
doi_str_mv | 10.1159/000065276 |
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Robert</creatorcontrib><creatorcontrib>Feldman, George M.</creatorcontrib><title>Successful Treatment of Steroid-Resistant Minimal Change Disease with Mycophenolate Mofetil</title><title>American journal of nephrology</title><addtitle>Am J Nephrol</addtitle><description>Mycophenolate mofetil has been reported to be effective in the treatment of steroid-responsive minimal change disease. We report a case of steroid- and cyclosporin-resistant minimal change disease with severe nephrotic syndrome that responded to mycophenolate mofetil with complete remission. The patient remains in complete remission 1 year after the discontinuation of mycophenolate mofetil. The presented case argues for the need of a prospective controlled study with the goal of evaluating the efficacy of mycophenolate mofetil in the therapy of steroid-resistant minimal change disease.</description><subject>Biological and medical sciences</subject><subject>Case Report</subject><subject>Drug Resistance</subject><subject>Humans</subject><subject>Immunomodulators</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mycophenolic Acid - analogs & derivatives</subject><subject>Mycophenolic Acid - therapeutic use</subject><subject>Nephrosis, Lipoid - drug therapy</subject><subject>Pharmacology. 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Robert</au><au>Feldman, George M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Successful Treatment of Steroid-Resistant Minimal Change Disease with Mycophenolate Mofetil</atitle><jtitle>American journal of nephrology</jtitle><addtitle>Am J Nephrol</addtitle><date>2002-09-01</date><risdate>2002</risdate><volume>22</volume><issue>5-6</issue><spage>569</spage><epage>572</epage><pages>569-572</pages><issn>0250-8095</issn><eissn>1421-9670</eissn><coden>AJNED9</coden><abstract>Mycophenolate mofetil has been reported to be effective in the treatment of steroid-responsive minimal change disease. We report a case of steroid- and cyclosporin-resistant minimal change disease with severe nephrotic syndrome that responded to mycophenolate mofetil with complete remission. The patient remains in complete remission 1 year after the discontinuation of mycophenolate mofetil. The presented case argues for the need of a prospective controlled study with the goal of evaluating the efficacy of mycophenolate mofetil in the therapy of steroid-resistant minimal change disease.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>12381961</pmid><doi>10.1159/000065276</doi><tpages>4</tpages></addata></record> |
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subjects | Biological and medical sciences Case Report Drug Resistance Humans Immunomodulators Immunosuppressive Agents - therapeutic use Male Medical sciences Middle Aged Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Nephrosis, Lipoid - drug therapy Pharmacology. Drug treatments Steroids - therapeutic use |
title | Successful Treatment of Steroid-Resistant Minimal Change Disease with Mycophenolate Mofetil |
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