Mechanisms of star fruit-induced acute renal failure

We have previously discovered that star fruit can induce oliguric acute renal failure. To investigate the mechanisms of star fruit-associated acute oxalate nephropathy, the nephrotoxic effect of star fruit was examined in both cellular experiments and animal models. We evaluated renal function, path...

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Veröffentlicht in:	Food and chemical toxicology 2008-05, Vol.46 (5), p.1744-1752
Hauptverfasser:	Fang, Hua-Chang, Lee, Po-Tsang, Lu, Pei-Jung, Chen, Chien-Liang, Chang, Tsu-Yuan, Hsu, Chih-Yang, Chung, Hsiao-Min, Chou, Kang-Ju
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Acute Kidney Injury - pathology Acute renal failure animal models Animals Apoptosis Averrhoa carambola Biological and medical sciences cell lines Cells, Cultured creatinine Creatinine - blood Creatinine - urine cultured cells deoxynucleotidyl transferase nick-end labeling dose response Dose-Response Relationship, Drug Enzymes - urine epithelium Flow Cytometry Fruit - chemistry Fruit - toxicity fruit juices genetic techniques and protocols histopathology In Situ Nick-End Labeling Kidney - pathology Kidney Function Tests Male mechanism of action Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure nephrotoxicity Oxalate Oxalates - blood Oxalates - urine oxalic acid Rats Rats, Sprague-Dawley Renal failure Star fruit temporal variation Toxicology tropical and subtropical fruits
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