Detrimental Effects of Nicotine and Endotoxin in the Newborn Piglet Brain during Severe Hypoxemia

Hypoxia-ischemia is a major cause of perinatal brain damage, but evidence shows that brain injury also is associated with intrauterine infections and maternal smoking. The mechanisms are not known, and we therefore explored the effects of experimental inflammation or nicotine on perinatal brain meta...

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