Clinical characteristics of PD patients with LRRK2 G2385R and R1628P variants

•a large sample of 721 PD patients of Chinese origin.•motor symptoms, non-motor symptoms and co-morbidities were analyzed in our study.•the relationship between the variants and clinical symptoms were analyzed. LRRK2 is the most common genetic cause of PD. G2385R and R1628 P variants are the most co...

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Veröffentlicht in:Neuroscience letters 2018-10, Vol.685, p.185-189
Hauptverfasser: Liang, Dongxiao, Shu, Li, Pan, Hongxu, Xu, Qian, Guo, Jifeng, Yan, Xinxiang, Tang, Beisha, Sun, Qiying
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Sprache:eng
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