The human papillomavirus (HPV)-related cancer biology: An overview

•Cancer is an important public health problem globally.•HPV is responsible for 30% of all infectious agent-related cancer.•Oncoproteins (E6 and E7) cooperate to promote carcinogenesis.•Oncoproteins can lead to metabolic deregulation and metastasis.•Novel therapeutic and prophylactic vaccines are man...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2018-10, Vol.106, p.1537-1556
Hauptverfasser:	Araldi, Rodrigo Pinheiro, Sant’Ana, Thalita Araujo, Módolo, Diego Grando, de Melo, Thatiana Correa, Spadacci-Morena, Diva Denelle, de Cassia Stocco, Rita, Cerutti, Janete Maria, de Souza, Edislane Barreiros
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer progression Cancer Vaccines - administration & dosage Cell Transformation, Viral Genotype Host-Pathogen Interactions HPV Humans Metastasis Mutation Neoplasms - metabolism Neoplasms - pathology Neoplasms - prevention & control Neoplasms - virology Oncogene Proteins, Viral - metabolism Oncology Papillomaviridae - genetics Papillomaviridae - metabolism Papillomaviridae - pathogenicity Papillomavirus Infections - metabolism Papillomavirus Infections - pathology Papillomavirus Infections - prevention & control Papillomavirus Infections - virology Papillomavirus Vaccines - administration & dosage Phenotype Prognosis Risk Factors
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