Regulation of the NFAT pathway discriminates CD4 super(+)CD25 super(+) regulatory T cells from CD4 super(+)CD25 super(-) helper T cells

CD4 super(+)CD25 super(+) regulatory T cells (Tregs) are potent modulators of immune responses. The transcriptional program distinguishing Tregs from the CD4 super(+)CD25 super(-) Th cells is unclear. NFAT, a key transcription factor, is reported to interact with forkhead box p3, allowing inhibitory...

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Veröffentlicht in:	Journal of leukocyte biology 2008-03, Vol.83 (3), p.708-717
Hauptverfasser:	Sumpter, T L, Payne, K K, Wilkes, D S
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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